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Postdoctoral Fellow - Structural Biology and Drug Discovery
About City of Hope
City of Hope is an independent biomedical research and treatment organization for cancer, diabetes and other life-threatening diseases.
Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope’s translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution. AccessHope™, a subsidiary launched in 2019 serves employers and their health care partners by providing access to City of Hope’s specialized cancer expertise.
A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation’s “Best Hospitals” in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.
City of Hope’s commitment to Diversity, Equity and Inclusion
We believe diversity, equity and inclusion is key in serving our mission to provide compassionate patient care, drive innovative discovery, and advance vital education focused on eliminating cancer and diabetes in all of our communities. Our commitment to Diversity, Equity and Inclusion ensures we bring the full range of skills, perspectives, cultural backgrounds and experiences to our work -- and that our teams align with the people we serve in order to build trust and understanding. We are dedicated to fostering a community that embraces diversity - in ideas, backgrounds and perspectives; this is reflected in our work and represented in our people.
We currently have a Postdoctoral Fellowship position within a research team headed by Dr. Jeff Perry, Assistant Professor, Department of Molecular Diagnostics and Experimental Therapeutics, and member of the City of Hope Comprehensive Cancer. We are looking for a post-doctoral candidate with experience in protein crystallography and/or biophysical methods that include isothermal calorimetry and surface plasmon resonance.
The Perry laboratory uses structural biology approaches, together with fragment-based drug discovery, computer-aided drug discovery approaches and biochemical assays to target key proteins driving carcinogenesis. This DoD funded position is for a postdoctoral trainee interested in aiding the development of cancer therapeutics against a novel therapeutic target.
Key Responsibilities include:
- Devise, plan, document and advance basic science-based projects in the area of structural biology and drug discovery.
- Generate data for grant applications and prepare manuscripts for publication.
- Work in close collaboration with other team members and external collaborators, including presentation of progress internally or externally.
- Train and supervise technical staff.
Basic education, experience and skills required for consideration:
- A Ph.D. in Biochemistry, Biophysics or a related discipline is required.
- Evidence of scientific rigor and excellence as documented by peer-reviewed publications.
- Ability to work in a fast-paced research environment and manage multiple projects and collaborations.
- Strong team player with excellent communication skills and fluency in English, both spoken and written.
As a condition of employment, City of Hope requires staff to comply with all state and federal vaccination mandates.
City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.
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