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RESEARCH SCIENTIST 3 (LAB MANAGER)

University of Washington

Job Description


As a UW employee, you have a unique opportunity to change lives on our campuses, in our state and around the world. UW employees offer their boundless energy, creative problem solving skills and dedication to build stronger minds and a healthier world.

UW faculty and staff also enjoy outstanding benefits, professional growth opportunities and unique resources in an environment noted for diversity, intellectual excitement, artistic pursuits and natural beauty. 

Department of Medicine, Pulmonary has an outstanding opportunity for a Research Scientist 3 (Lab Manager).

Field of research:  Organ Dysfunction in the critically ill population with particular focus on kidney and pulmonary injury

Funding sponsors:  NIH, private sponsors

The purpose of this Research Scientist 3 (1.0 FTE) lab manager position, based in Dr. Pavan Bhatraju's laboratory at the UW Harborview Medical Center Research campus, is to investigate risk of development of organ dysfunction in the critically ill population with particular focus on kidney and pulmonary injury. Projects involve processing of primary human blood and urine, completing biomarker measurements and human genotyping. We are investigating diseases such as sepsis, COVID-19 and acute kidney injury.

The Bhatraju laboratory is located within the Sepsis Center of Research Excellence (SCORE) and as the laboratory manager of the Bhatraju research group, the Research Scientist 3 (lab manager) will also engage with collaborating SCORE laboratory personnel including investigators, trainees and staff.

Working under the general direction of the principal investigator the Research Scientist 3 (lab manager) will directly conduct extramurally funded research and be responsible for the day to day laboratory operations.

Laboratory operations and management responsibilities will include establishing a schedule for experiment completion, assigning duties to a research scientist assistant and hourly employees, evaluating results, training other laboratory members on experimental protocols and specific laboratory techniques.  The laboratory manager will also be expected to contribute to development of research protocols and strategies for proposed lines of investigation, and assist postdoctoral fellows with onboarding into the laboratory environment.

RESPONSIBILITIES:

In addition, the duties below will need to be worked on – both for the percent effort for each area and to repeat the specific lab management/operations duties below.

Specimen processing and management (50%):

• Map large sample sets, run RT-PCR Genotyping assays on QuantStudio7 RT-PCR instrument
• Run Meso-Scale Discovery (MSD) biomarker analysis
• Process, subaliquot and analyze COVID-19 and non-COVID-19 patient samples in BSL-2 environment
• Develop and accurately reproduce laboratory protocols
• Train and oversee other members of the laboratory group on techniques and processes
• ELISA assays

Data Analysis (30%):

• Analyze raw data using MDS regression software
• Sample search in Freezerworks specimen management databases for further biochemical analysis
• Access data in other institutional databases (e.g., REDCap) when required
• Produce analysis for use in publications and sponsor reports

Laboratory management (20%):

• Maintain meticulous laboratory documentation
• Inventory and track supplies, orders and deliveries
• Maintain freezer map
• Assist with other laboratory management duties as required

MINIMUM REQUIREMENTS:

Bachelor's degree in Molecular, Cellular and Development Biology or similar field of study with at least 3 years of relevant experience.

Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration.

ADDITIONAL REQUIREMENTS:

• Experience in using RT-PCR System for SNP detection and qPCR analysis
• Familiarity with ELISA-type assays (Meso Scale Discovery)
• Ability to analyze large data sets

DESIRED:

• Ability to be highly flexible, effectively change direction in constantly evolving environment by taking on new and unexpected responsibilities.
• Effective communicator and strong team player
• Focused on the team and deliverables concurrently.

Application Process:
The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process.  These assessments may include Work Authorization, Cover Letter and/or others.  Any assessments that you need to complete will appear on your screen as soon as you select “Apply to this position”. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment you will be prompted to do so the next time you access your “My Jobs” page. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.


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