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Research Fellow - Cancer Center

Job Description

Research Fellow - Cancer Center

Job Req ID : (3208875)

Primary Location MA-Charlestown-MGH 13th Street

Work Locations MGH 13th Street 149 13th Street Charlestown 02129
Job MD/PHD/Fellows/ PostDocs
Organization Massachusetts General Hospital(MGH)
Schedule Full-time
Standard Hours 40
Shift Day Job
Employee Status Regular
Recruiting Department MGH Cancer Center
Job Posting Aug 2, 2022

Full Job Description

Massachusetts General Hospital Cancer Center and

Harvard Medical School

Postdoctoral fellowship position is available within Mass General Hospital, a Harvard Medical School teaching hospital. Mass General comprises the largest hospital-based academic research program in the US. The goal of the Jan Lab is to conduct science with the potential to directly enhance the safety, efficacy, and accessibility of anti-cancer cell therapies. To this end, the Jan Lab uses targeted protein degradation to develop novel concepts in synthetic biology and immune cell engineering. Recent studies include the creation of clinically suitable lenalidomide-inducible dimerization and degradation systems, and with them lenalidomide ON- and OFF-switch CAR T cells (Science Translational Medicine (2021): 13.575 and Nature Reviews Clinical Oncology (2021): 1-17). Topics of major interest include ubiquitin-dependent control of immune cell function, synthetic biology creation by reprogramming protein degradation, and the engineering of novel cellular immunotherapies. Partnership with the laboratory of Dr. Marcela Maus and the MGH Cellular Immunotherapy Program enable a direct path to translate advances to the care of patients at MGH.

The Jan Lab is a part of the MGH Center for Cancer Research and Department of Pathology. The position provides a rich intellectual environment with full integration into the excellent research communities of MGH and Harvard. The lab prioritizes trainee wellbeing, professional development, and fostering a diverse, inclusive, collaborative, and creative environment. A multidisciplinary group, the lab integrates molecular biology, immunology, genomics, and biochemistry. Key qualifications include the completion of doctoral training in the biomedical sciences, strong publication records, and most importantly passion for biomedical research. To read more about current research topics and mentorship statement please visit: janlabmgh.org.

Please send CV and cover letter to: Dr. Max Jan at: mjan@mgh.harvard.edu.

Massachusetts General Hospital and Harvard Medical School uphold a commitment to affirmative action and equal opportunity.

Massachusetts General Hospital complies with applicable Federal civil rights laws and does not discriminate against any individual regardless of race, color, religious creed, gender, gender identity or expression, genetic information, sexual orientation, age, disability, veteran or active military status, marital status, national origin/ethnicity, citizenship or immigration status.

Massachusetts General Hospital Cancer Center and

Harvard Medical School

Postdoctoral fellowship position is available within Mass General Hospital, a Harvard Medical School teaching hospital. Mass General comprises the largest hospital-based academic research program in the US. The goal of the Jan Lab is to conduct science with the potential to directly enhance the safety, efficacy, and accessibility of anti-cancer cell therapies. To this end, the Jan Lab uses targeted protein degradation to develop novel concepts in synthetic biology and immune cell engineering. Recent studies include the creation of clinically suitable lenalidomide-inducible dimerization and degradation systems, and with them lenalidomide ON- and OFF-switch CAR T cells (Science Translational Medicine (2021): 13.575 and Nature Reviews Clinical Oncology (2021): 1-17). Topics of major interest include ubiquitin-dependent control of immune cell function, synthetic biology creation by reprogramming protein degradation, and the engineering of novel cellular immunotherapies. Partnership with the laboratory of Dr. Marcela Maus and the MGH Cellular Immunotherapy Program enable a direct path to translate advances to the care of patients at MGH.

The Jan Lab is a part of the MGH Center for Cancer Research and Department of Pathology. The position provides a rich intellectual environment with full integration into the excellent research communities of MGH and Harvard. The lab prioritizes trainee wellbeing, professional development, and fostering a diverse, inclusive, collaborative, and creative environment. A multidisciplinary group, the lab integrates molecular biology, immunology, genomics, and biochemistry. Key qualifications include the completion of doctoral training in the biomedical sciences, strong publication records, and most importantly passion for biomedical research. To read more about current research topics and mentorship statement please visit: janlabmgh.org.

Please send CV and cover letter to: Dr. Max Jan at: mjan@mgh.harvard.edu.

Massachusetts General Hospital and Harvard Medical School uphold a commitment to affirmative action and equal opportunity.

Massachusetts General Hospital complies with applicable Federal civil rights laws and does not discriminate against any individual regardless of race, color, religious creed, gender, gender identity or expression, genetic information, sexual orientation, age, disability, veteran or active military status, marital status, national origin/ethnicity, citizenship or immigration status.

EEO Statement


Massachusetts General Hospital is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. Applications from protected veterans and individuals with disabilities are strongly encouraged.

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