Postdoctoral Fellow - Neurodegenerative Disorders
Job ID : 42083
Location : Columbia
Full/Part Time : Full-Time
Postdoc position in immunology for microbiome-gut-brain axis in Alzheimer’s disease and other neurodegenerative disorders
PI: Ai-Ling Lin, PhD
The Lin Brain Lab at the University of Missouri (MU) has a focus on understanding the microbiome-gut-brain axis in neurodegenerative disorders, including Alzheimer’s disease, stroke, and traumatic brain injury. We also focus on developing effective nutritional and pharmacological interventions to mitigate risk for those neurodegenerative disorders in humans and animals. Our research involves both animal works and clinical applications, to translate our findings from the bench to the bed side.
We apply wide range of technology in our research, including shotgun metagenomics sequencing, metabolomics, artificial intelligence, and prebiotics/probiotics manufactures. We also use neuroimaging, such as magnetic resonance imaging (MRI) and positron emission tomography (PET), to understand the impact of microbiome changes on brain structural, vascular, and metabolic functions. We are extending our understanding of immune responses to gut dysbiosis in neurological diseases and the potential changes with interventions.
We seek a postdoctoral candidate who has expertise in immunology and is versed with technology for inflammatory marker measurements, especially for neuroinflammation. The work will take place at the newly built, state-of-the-art NextGen Precision Health Building of the University of Missouri in Columbia, MO. MU has strong programs and resources support in Molecular Microbiology and Immunology (MMI), and the state-of-the-art facility in the Metagenomics Center, Metabolomics Center, Food Engineering Unit, and translational MRI and PET imaging center. MU is a very collaborative environment; the candidate will have ample opportunities to work with faculty and students across different departments and units, including MMI, Radiology and Biological Sciences. The candidate will also have opportunity to learn new technology outside his/her field (e.g., MRI and PET imaging processing), and receive mentoring from the PI and other faculty to develop his/her own independent research programs and grant applications.
• Perform bioassays, such as immunohistology PCR, qPCR, ELISAs, western blots, and DNA extraction
• Perform gut microbiome analysis and understand the correlations between gut microbiome changes and immunity responses.
• Data storage and organization in databases, preparation of summary of results, preparation of manuscript and presentations
• Maintain accurate records of research activity and contribute to writing of protocol documents
• Adhere to safety protocols and maintain lab in clean and high-functioning condition
• Mentoring and training junior lab members
• Pursuit of research and other scholarly activities, such as manuscript and grant writing
• PhD in immunology, microbiology, neuroscience, biochemistry or similar field, or MD/PhD
Candidates will be evaluated on:
• Experiences on grant writings
• Experiences on R or Python
• Proficiency in statistical analysis
• Track record of scientific productivity such as publications
• Works well in collaborative teams and able to manage an independent research project
• Excellent writing and communicating skills
Online Application, Cover Letter, CV, and a list of 3 References
This position is eligible for University benefits. The University offers a comprehensive benefits package, including medical, dental and vision plans, retirement, and educational fee discounts. For additional information on University benefits, please visit the Faculty & Staff Benefits website at http://www.umsystem.edu/totalrewards/benefits
The University of Missouri is fully committed to achieving the goal of a diverse and inclusive academic community of faculty, staff and students. We seek individuals who are committed to this goal and our core campus values of respect, responsibility, discovery and excellence.
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Columbia Missouri Information
Columbia, Mo., is known as an ideal college town, combining small-town comforts, community spirit and low cost of living with big-city culture, activities and resources. Home to nationally renowned public schools and other colleges and educational centers, Columbia is packed with restaurants and entertainment venues and hosts more than a dozen annual cultural festivals.
After careful consideration of COVID-19 virus trends and the overwhelming evidence of COVID-19 vaccine safety and effectiveness, the School of Medicine, along with MU Health Care, the Sinclair School of Nursing and the School of Health Professions, recently announced the decision to require COVID-19 vaccinations by Oct. 1, 2021, for all employees, unless granted a medical or religious exemption.
All new hires will be required to submit proof of vaccination prior to your start date. If you would like to request a medical or religious exemption, you must do so upon acceptance of employment so our team has time to review prior to your scheduled start date. You will not be allowed to begin work until you have submitted proof of vaccination or received an approved medical or religious exemption.
Thank you for helping us to create the safest environment possible for our colleagues, students and our patients by protecting yourself and others through COVID-19 vaccination.
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