Harvard Medical School
Research Assistant – Brugge Laboratory
Harvard Medical School Boston, MA
The Brugge lab has a long-standing interest in studying breast cancer using innovative techniques, with the ultimate goal to help improve treatment strategies for patients. We are looking for a highly motivated research assistant to join our team. As a research assistant, you will be working on projects that investigate the mechanisms of breast cancer initiation and progression using organoid culture systems and advanced mouse models, under direct supervision and mentorship of a senior postdoctoral fellow.
TECHNICAL DUTIES AND RESPONSIBILITIES:
• Optimizes human breast organoid culture conditions from primary samples;
• Introduces genetic alterations of interest in organoid cultures using CRISPR/Cas9 technology;
• Tests the effects of genetic alterations on organoid cultures using various assays that assess transformation;
• Assists in the design of laboratory experiments, techniques, and protocols;
• May instruct other staff and students in basic laboratory techniques; Performs related laboratory maintenance such as maintaining and cleaning equipment and ordering supplies;
• Cell and tissue immunostaining, microscopy, image analysis;
• Flow cytometry and FACS cell sorting;
• Molecular biology, e.g. plasmid cloning, gene expression and knockdown, qRT-PCR, western blots;
• Maintaining accurate and detailed record of experimental results.
Former technicians in the lab have successfully moved on to MD and/or PhD programs as well as industry positions.
Bachelor's degree in biological sciences or related field.
Additional Qualifications and Skills
Minimum 1 year experience in a research laboratory setting strongly preferred.
Experience in one or more of the following is preferred: mouse handling, cell culture, microscopy.
Highly motivated, good work ethic, and able to work independently and as a team.
Follow protocols with attention to detail.
Produce accurate and high-quality work.
Think creatively to solve problems.
Excellent skills in communication, organization, and time management.
This is a 2-year benefits eligible term position, contingent on work performance and continued funding to support the position. The department is requiring a 2-year commitment to this position.
Offer contingent on successful completion of pre-placement medical evaluation.
The University requires all Harvard community members to be fully vaccinated against COVID-19 and remain up to date with COVID-19 vaccine boosters, as detailed in Harvard’s Vaccine & Booster Requirements . Individuals may claim exemption from the vaccine requirement for medical or religious reasons. More information regarding the University’s COVID vaccination requirement, exemptions, and verification of vaccination status may be found at the University’s “COVID-19 Vaccine Information” webpage: http://www.harvard.edu/coronavirus/covid-19-vaccine-information/ .
Please note that we are currently conducting a majority of interviews and onboarding remotely and virtually. We appreciate your understanding.
Harvard University offers an outstanding benefits package including:
The Harvard Medical School is not able to provide visa sponsorship for this position.
- Time Off: 3 - 4 weeks paid vacation, paid holiday break, 12 paid sick days, 12.5 paid holidays, and 3 paid personal days per year.
- Medical/Dental/Vision: We offer a variety of excellent medical plans, dental & vision plans, all coverage begins as of your start date.
- Retirement: University-funded retirement plan with full vesting after 3 years of service.
- Tuition Assistance Program: Competitive tuition assistance program, incredibly affordable classes directly at the Harvard Extension School, and discounted options through participating Harvard grad schools.
- Transportation: Harvard offers a 50% discounted MBTA pass as well as additional options to assist employees in their daily commute.
- Wellness options: Harvard offers programs and classes at little or no cost, including stress management, massages, nutrition, meditation, and complementary health services.
- Harvard access to athletic facilities, libraries, campus events, and many discounts throughout metro Boston.
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USA - MA - Boston
403112 Research Assistant II Lab
55 - Hvd Union Cler & Tech Workers
Criminal, Education, Identity
35 hours/week | Monday-Friday
Commitment to Equity, Diversity, Inclusion, and Belonging
We are committed to cultivating an inclusive workplace culture of faculty, staff, and students with diverse backgrounds, styles, abilities, and motivations. We appreciate and leverage the capabilities, insights, and ideas of all individuals. Harvard Medical School Mission and Community Values
We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions, or any other characteristic protected by law.