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The Department of Genome Sciences (GS) is part of the University of Washington School of Medicine (UW SoM) and is comprised of 26 labs addressing leading edge questions in biology and medicine by developing and applying genetic, genomic and computational approaches taking advantage of genomic information now available for a host of species. GS is making major contributions in the application of genome science to understand the fundamentals of biology and to improve human health and wellbeing. Genome Sciences is a collaborative department supported by very different academic disciplines. We work with a multitude of Program Investigators (PIs) in departments both on the UW campus as well as worldwide. The department has gone through significant expansion since its beginning in 2001 with annual grant awards of $68.5M in FY21.
The Department of Genome Sciences is committed to creating an environment that is welcoming and inclusive. Our goal is to foster a place of learning and working where all members can thrive and where diversity is recognized and celebrated. At Genome Sciences, we aim to create supportive spaces for those who are marginalized in higher education or society. To achieve this, we recognize that it is our ongoing responsibility to understand, acknowledge, and challenge systems of privilege and disadvantage in higher education such as those based on race, color, creed, caste, religion, national origin, citizenship, sex, age, marital status, sexual orientation, gender identity or expression, disability, veteran status, or socioeconomic status.
This is an exciting opportunity for a Research Scientist/Engineer Assistant, Long-Read DNA Sequencing to contribute to projects investigating the role of genomic structural variation in human disease and primate evolution, the genetic architecture of autism, and understanding natural genome variation between humans and other primates. The Research Scientist/Engineer Assistant will learn to use cutting-edge techniques in next-generation and long-read DNA and RNA sequencing to generate genomic and transcriptomic data for lab projects and the broader scientific community.
Actively contribute to the research results of the laboratory. Work collaboratively to support other researchers; assist graduate students and postdoctoral fellows on multiple on-going research projects. Follow instructions and lab protocols to perform routine scientific investigative procedures and maintain accurate records. Complete assigned tasks on time to achieve tight production deadlines.
Research and Data Analysis, UW PacBio Sequencing Services (70%):
o Library preparation, sequencer operation, and other duties to support single-molecule, real-time (SMRT) sequencing research projects on the Sequel II instruments associated with UW PacBio Sequencing Services. Full hands-on training provided, if necessary. See: https://pacbio.gs.washington.edu/
o Meticulous sample tracking and database maintenance.
o Learn to perform routine analysis of data using a web interface.
Sample Preparation (20%):
o Generate high quality nucleic acid material for long- and short-read sequencing applications.
o DNA and RNA isolation from various sources including cell culture, tissue, and blood.
o Bacterial and mammalian cell culture.
Additional Sequencing Support (5%):
o Provide support for long-read sequencing projects using Oxford Nanopore Technology sequencing platforms.
o Provide support for short-read sequencing projects as needed.
Perform related duties as required. (5%)
• Bachelor’s degree in Biology, Biochemistry, Microbiology or related Life Sciences field OR equivalent education/experience.
• 0 to 3 months laboratory research experience.
• Able to work independently and as part of a multidisciplinary team.
• Able to learn new techniques.
• Attention to detail and strong organizational abilities.
• Demonstrated commitment to valuing diversity and contributing to an inclusive working and learning environment.
• Basic computing skills using Microsoft Word, Excel, and PowerPoint, or Google Docs and Sheets.
Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration.
• Some laboratory experience in a research or industry setting.
• Experience and knowledge of the fundamental concepts, practices and procedures required for working in a genomics laboratory.
• Exposure to next-generation (Illumina) sequencing and genomics laboratory techniques.
• Experience with UNIX/*NIX command line, BASH shell scripting, R, and/or Python.
Applicants who are eager to learn that don’t possess all of above are still encouraged to apply! This position presents a great opportunity for professional growth.
As a UW employee, you will enjoy generous benefits and work/life programs. For detailed information on Benefits for this position, click here.
The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Workforce Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select “Apply to this position”. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment you will be prompted to do so the next time you access your “My Jobs” page. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.