We invite applications for a post-doctoral position, funded by the NIH and Helmsley Charitable Trust, focusing on cryo-EM studies of how insulin analogs bind to the insulin receptor. Analogs include ultra-stable and glucose-responsive insulin variants of clinical interest. The Indiana University School of Medicine (IUSM) has an EM Core with 200 kEV Glacios cryo-EM system and shared access to a 300 kEV Titan Krios, located at Purdue University as part of a regional consortium. The post-doctoral fellow will be part of a multidisciplinary team including synthetic peptide chemists and cell biologists engaged in insulin research with translational application to the improved treatment of diabetes mellitus. A PhD in structural biology or computation protein chemistry is required. Prior experience with cryo-EM is preferred but not required. IUSM provides a diverse international community and welcomes applications from scientists of diverse backgrounds, cultures, nationalities and genders. Non-US Citizens will require an appropriate Visa for employment in the United States. Please send Curriculum Vitae, letter of introduction and names of three referees (including prior or current laboratory mentors) to: Drs. Yuichiro Takagi and Michael A. Weiss, Department of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202 (email addresses ytakagi@iu.edu and weissma@iu.edu).
As the nation’s largest medical school, IUSM is committed to being an institution that not only reflects the diversity of the learners we teach and the patient populations we serve, but also pursues the values of diversity, equity and inclusion that inform academic excellence. We desire candidates who enhance our representational diversity, as well as those whose work contributes to equitable and inclusive learning and working environments for our students, staff, and faculty. IUSM strives to take an anti-racist stance, regularly evaluating and updating its policies, procedures, and practices to confer equitable opportunities for contribution and advancement for all members of our community. We invite individuals who will join us in our mission to advance racial equity to transform health and wellbeing for all throughout the state of Indiana. More information about diversity and inclusion efforts at IUSM can be found at https://faculty.medicine.iu.edu/diversity.
Basic Qualifications
Doctorate or terminal degree required. PhD required with relevant experience in protein expression and purification. Experience with funded for at least three years by the NIH
Department Contact for Questions
Dr. Joseph D Racca, PhD
jracca@iu.edu
Additional Qualifications
Special Instructions
Priority Application Review Deadline
Expected Start Date
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