Position Summary

Acute kidney injury causes high mortality via its secondary organ effects. The postdoctoral fellow will study interorgan crosstalk, in particular of kidney-heart-lung, using organ injury models in mice. They will use state-of-the-art technologies, such as single cell/single nucleus RNAseq, proteomics (mass cytometry and mass spectrometry), to discover mediators of interorgan crosstalk. Mediators will be targeted with antibodies, drugs and in transgenic mice. Initial single cell RNAseq experiments of kidney and lung in kidney-injured mice have already been done and the computational RNAseq analysis pipeline is established in the lab.

Visit the Office of Postdoctoral Affairs  for more information about being a postdoc at Washington University in St. Louis.

Primary Duties & Responsibilities

• In collaboration with the PI, performs studies of interorgan crosstalk in injury models in mice in vivo and in vitro in cell lines.
• Analyzes and reports data to the PI.
• Works with mice and oversees their own mouse colony and breeding schemes.
• Performs mouse surgeries.
• Assists with grant preparation and reporting.
• Prepares and submits papers on research.
• Assists in the design of research experiments.
• Evaluates research findings and assists in the reporting of the results.
• Maintains conscientious discharge of their research responsibilities.
• Maintains conformity with ethical standards in research.
• Maintains compliance with good laboratory practice, including the maintenance of adequate research records.
• Engage in open and timely discussion with their mentor regarding possession or distribution of material, reagents, or records belonging to their laboratory and any proposed disclosure of findings or techniques privately or in publications.
• Maintains collegial conduct towards co-trainees, staff members, and members of the research group.
• Adheres to all applicable University policies, procedures, and regulations.  All data, research records, materials, and other intellectual property generated in University laboratories remain the property of the University.

Required Qualifications

Ph.D., M.D. or equivalent terminal or doctoral degree.

Preferred Qualifications

Prior experience with mouse handling and surgeries is desirable.

Working Conditions

This position works in a laboratory environment with potential exposure to biological and chemical hazards.  The individual must be physically able to wear protective equipment and to provide standard care to research animals.

Salary Range

Base pay is commensurate with experience.

Applicant Special Instructions

To apply, please send your resume to Dr. Andreas Herrlich at aherrlich@wustl.edu .

Pre-Employment Screening
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.

Benefits Statement
Washington University in St. Louis is committed to providing a comprehensive and competitive benefits package to our employees. Benefits eligibility is subject to employment status, full-time equivalent (FTE) workload, and weekly standard hours. Please visit our website at https://hr.wustl.edu/benefits/ to view a summary of benefits.

EEO/AA Statement
Washington University is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration without regard to an individual’s sex, race, color, religion, age, disability status, protected veteran status, national or ethnic origin, gender identity or expression, sexual orientation. Women, minorities, protected veterans and the disabled are strongly encouraged to apply.

Diversity Statement
Washington University is dedicated to building a diverse community of individuals who are committed to contributing to an inclusive environment – fostering respect for all and welcoming individuals from diverse backgrounds, experiences and perspectives. Individuals with a commitment to these values are encouraged to apply.

Job Description

Position Summary

Acute kidney injury causes high mortality via its secondary organ effects. The postdoctoral fellow will study interorgan crosstalk, in particular of kidney-heart-lung, using organ injury models in mice. They will use state-of-the-art technologies, such as single cell/single nucleus RNAseq, proteomics (mass cytometry and mass spectrometry), to discover mediators of interorgan crosstalk. Mediators will be targeted with antibodies, drugs and in transgenic mice. Initial single cell RNAseq experiments of kidney and lung in kidney-injured mice have already been done and the computational RNAseq analysis pipeline is established in the lab.

Visit the Office of Postdoctoral Affairs  for more information about being a postdoc at Washington University in St. Louis.

Primary Duties & Responsibilities

• In collaboration with the PI, performs studies of interorgan crosstalk in injury models in mice in vivo and in vitro in cell lines.
• Analyzes and reports data to the PI.
• Works with mice and oversees their own mouse colony and breeding schemes.
• Performs mouse surgeries.
• Assists with grant preparation and reporting.
• Prepares and submits papers on research.
• Assists in the design of research experiments.
• Evaluates research findings and assists in the reporting of the results.
• Maintains conscientious discharge of their research responsibilities.
• Maintains conformity with ethical standards in research.
• Maintains compliance with good laboratory practice, including the maintenance of adequate research records.
• Engage in open and timely discussion with their mentor regarding possession or distribution of material, reagents, or records belonging to their laboratory and any proposed disclosure of findings or techniques privately or in publications.
• Maintains collegial conduct towards co-trainees, staff members, and members of the research group.
• Adheres to all applicable University policies, procedures, and regulations.  All data, research records, materials, and other intellectual property generated in University laboratories remain the property of the University.

Required Qualifications

Ph.D., M.D. or equivalent terminal or doctoral degree.

Preferred Qualifications

Prior experience with mouse handling and surgeries is desirable.

Working Conditions

This position works in a laboratory environment with potential exposure to biological and chemical hazards.  The individual must be physically able to wear protective equipment and to provide standard care to research animals.

Salary Range

Base pay is commensurate with experience.

Applicant Special Instructions

To apply, please send your resume to Dr. Andreas Herrlich at aherrlich@wustl.edu .

Pre-Employment Screening
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.

Benefits Statement
Washington University in St. Louis is committed to providing a comprehensive and competitive benefits package to our employees. Benefits eligibility is subject to employment status, full-time equivalent (FTE) workload, and weekly standard hours. Please visit our website at https://hr.wustl.edu/benefits/ to view a summary of benefits.

EEO/AA Statement
Washington University is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration without regard to an individual’s sex, race, color, religion, age, disability status, protected veteran status, national or ethnic origin, gender identity or expression, sexual orientation. Women, minorities, protected veterans and the disabled are strongly encouraged to apply.

Diversity Statement
Washington University is dedicated to building a diverse community of individuals who are committed to contributing to an inclusive environment – fostering respect for all and welcoming individuals from diverse backgrounds, experiences and perspectives. Individuals with a commitment to these values are encouraged to apply.