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Research Scientist
University of Pittsburgh in Pittsburgh, Pennsylvania
 
 
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Date Posted 01/15/2022
Category
Admin-Laboratory and Research
Employment Type
Application Deadline Open until filled
 
 
 
 
 

Research Scientist
UPCI Research Lab-Shlomchik, Warren - Pennsylvania-Pittsburgh - (22000412)
 

The University of Pittsburgh is seeking a Research Scientist to work in the laboratory of Dr. Warren Shlomchik at the UPMC Hillman Cancer Center. The candidate will study the mechanisms whereby interferon-gamma sensitizes leukemia cells to killing by alloreactive T cells. The project employs CRISPR-editing of novel mouse leukemia lines derived from compound oncogene knockin mice, single cell RNA sequencing, ATAC-seq, in vivo studies with novel T cell receptor transgenic mice, and CRISPR-Cas9-screens to identify genes that both render leukemia cells resistant to T cell killing.  Specific skills and knowledge that are essential for the position:1)      Knowledge of immunology, particularly cellular immunology is highly valued2)      Knowledge of malignant hematology is highly valued3)      Experience with mouse handling4)      Experience with CRISPR-Cas9 genome editing5)      Expertise in multi-parameter flow cytometry6)      Expertise in common molecular biology techniques including modern cloning, PCR, RT-PCR. 

 

PhD in a biological science with 5 years of postdoctoral training preferred. Specific skills and knowledge that are essential for the position:1)      Knowledge of immunology, particularly cellular immunology is highly valued2)      Knowledge of malignant hematology is highly valued3)      Experience with mouse handling4)      Experience with CRISPR-Cas9 genome editing5)      Expertise in multi-parameter flow cytometry6)      Expertise in common molecular biology techniques including modern cloning, PCR, RT-PCR. 

 The University of Pittsburgh is an Affirmative Action/Equal Opportunity Employer and values equality of opportunity, human dignity and diversity. EOE, including disability/vets The University of Pittsburgh requires all Pitt constituents (employees and students) on all campuses to be vaccinated against COVID-19 or have an approved exemption. Visit coronavirus.pitt.edu to learn more about this requirement. 
Assignment Category: Full-time regular
Job Classification: Staff.Research Scientist.Scientist
Campus: Pittsburgh
Minimum Education Level Required: PhD or ScD
Minimum Experience Level Required: 3-5 years experience
Work Schedule: Monday - Friday, 8:30 a.m. - 5:00 p.m.
Hiring Range: $46,644.00 - $76,440.00
Relocation Offered: No
Visa Sponsorship Provided: No
Background Check: For position finalists, employment with the University will require successful completion of a background check
Child Protection Clearances: Not Applicable
Required Documents: Resume
Optional Documents: Cover Letter
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