Posting Number
046138  
Position Title
Post-Doctoral Fellow  
Number of Vacancies
1  
School/College/Division/Institutes/Centers
18 - Pharmacy and Health Sciences  
Primary Department
H1822-Pharmaceutical Sciences  
Working Conditions
Wayne State University requires all students, faculty and staff to be fully vaccinated against COVID-19 with limited exceptions. Learn more at: https://wayne.edu/coronavirus
Typical work environment may include a laboratory and/or office environment. May require working non-standard business hours including evenings and weekends. May be required to travel to scientific conferences.  
Essential Functions (Job Duties)
A new NIH-funded position is available for postdoctoral candidates with experience in conducting drug screening assays, molecular pharmacology experiments, and in vivo pharmacology studies. The chosen candidate's work will identify chemical compounds with desirable biological activity profiles that are suitable for escalation within the drug development process. The research fellow is expected to work independently on assigned projects and contribute substantially or wholly to their conception, experimental designs, data generation and analysis, and presentation. The postdoctoral fellow's research will yield reproducible findings pertaining to the biological actions of drug-like molecules and communicate such findings in scientific publications, patent filings, and grant submissions under the guidance of the PI.
Lab webpage: www.gavandelab.com
Essential Functions May Include:
Perform scientific techniques or research protocols. Assist the Principal Investigator in designing and performing protocols. Design and perform experiments. Collect and log research data. Participate in implementing research objectives, ensuring compliance with all legal, regulatory and protocol guidelines. Assist other lab members with experiments as required. May mentor research assistants and students.
With the assistance of the mentor, find and write research grants with the goal of obtaining additional research grant funding. Responsibilities may also include coordinating correspondence with applicants and grantees, acknowledging receipts of proposals, and maintaining a system to track proposals.
Evaluate and perform preliminary analysis of the data using graphs, charts or tables to highlight the key points of the research results collected in accordance with the research protocols as stipulated.
Prepare and present presentations regarding research project results for professional, scientific and academic conferences. Summarize and organize data results for submittal to academic and scholarly, peer-reviewed journals. Write scientific manuscripts and other documents for publication. Fact-check, proofread, and edit research documents to ensure accuracy.
Maintain the laboratory work areas including routine maintenance on laboratory equipment as required. Order and organize required research supplies and records. Maintain cleanliness and organization of work station.
Perform other related duties as assigned.  
Unique Duties
 
Qualifications
Doctorate degree
Requires advanced knowledge in a field of science or learning, predominantly intellectual in character. This knowledge is acquired by a prolonged course of specialized intellectual instruction.
3 to 4 years job-related experience. Job related experience can include doctorate training. Experience performing basic research techniques, preferred. Must have distinguished themselves in research. Prior recipient of funding for research based on individual achievements.
Ability to work independently. Ability to secure grants and funding for research. Ability to collect, analyze, summarize and interpret research findings in reports and communicate results to the field. Knowledge of and experience with current scientific integrity principles. Excellent time management and organization skills. Excellent interpersonal skills and demonstrated ability to work with others in a collaborative environment. Microsoft office software skills.  
Preferred Qualifications
A doctoral degree or equivalent (Ph.D., M.D., ScD., D.V.M., DDS etc) in an appropriate field.
Experience with cell culture techniques, molecular biology techniques (FP, ELISA, FRET, BRET, gel electrophoresis, enzyme inhibition assays), biophysical techniques (SPR, ITC), tumor xenograft models, and genetically modified mouse models.
Preference is shown for candidates with a strong track record in cancer drug discovery/translational research. Previous experience with experimental techniques for the characterization of PROTACs is an additional plus.
Experience with target deconvolution using molecular pharmacology & biophysical techniques.
Experience in conducting combination drug studies in cellulo and in vivo for evaluating synergy and antagonism.
Demonstrable experience with spheroid (3D) viability assays or other in vitro assays that mimic the human tumor microenvironment (e.g. immune cell-based functional assays) is preferred.
Experience with nucleic acid techniques such as PCR, ChIP-seq, RNAseq, Sanger Sequencing, and next-generation sequencing techniques is a plus.
Ability to generate stably transfected cell lines for use in high-throughput drug screening assays is preferred. Demonstrated ability to effectively interact and communicate in multidisciplinary project teams, including strong verbal, written communication, and presentation skills.
Excellent organization and planning skills, the ability to work in a fast-paced environment independently and as part of a team, and strong motivation with a dedicated work ethic.  
Testing Requirements
Not Applicable  
Test Scheduling
 
Job Type
Full-Time  
Job Category
Research Assistants/Associates  

Fiscal Year of Job Open Date
2022  
Job Open Date
(When job is posted in the system)
01-10-2022  
Job Close Date
(or until suitable candidate is found)
Until Suitable Candidate is Found
Is this position reposted?
No  
Reposting Reason:
None (New Posting)  

Background Check Requirements
University policy requires certain persons who are offered employment to undergo a background check, including a criminal history check, before starting to work. If you are offered employment, the University will inform you if a background check is required.  
Instructions for submitting your application:
Interested applicants should upload to this posting and submit a cover letter indicating availability, CV, statement of research interests, and contact information for three references electronically to Dr. Navnath Gavande at ngavande@wayne.edu. Review of applications will begin immediately and continue until the position is filled.  
Represented Position Message
 

Salary (Minimum)
(Non-Academic Only)
 
Salary (Hire Max)
(Non-Academic Only)
 
Salary (Maximum)
(Non-Academic Only)
 
Hourly Rate
(Non-Academic Only)
 
Salary Range
(Academic Only)
 
Is Position Bump Ineligible?
(Non-Academic, Represented positions only. Select 'No' for Academic. Select N/A if Non-represented.)
**NOTE: If 'Yes' is selected, then this is a Bump Ineligible Position (BIP). The person who bids or hires into this 100% grant funded position has no bumping rights upon grant expiration or in a reduction of force.
N/A