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Postdoctoral Associate
Rutgers University in New Brunswick, New Jersey
Date Posted 11/04/2021
Admin-Other Administrative Positions
Employment Type
Application Deadline Open until filled

Position Details
Recruitment/Posting Title Postdoctoral Associate
Department SAS-DLS-Cell Bio & Neurosci
Salary Commensurate With Experience
Posting Summary
Postdoctoral positions are available in the laboratory of Dr. Peng Jiang in the Department of Cell Biology and Neuroscience, Rutgers University New Brunswick.
The research focus of the Jiang ab is on investigating cellular and molecular basis of human brain development and pathogenesis of neurological disease utilizing human induced pluripotent stem cells (hiPSCs). We have been studying mechanisms of neurodevelopmental and neurodegenerative disorders and developing new therapeutics using novel hiPSC-based in vitro brain organoid and in vivo human-mouse chimeric brain models. We use a combination of multidisciplinary techniques in our research, including stem cell reprogramming, electrophysiology/patch-clamp recording, imaging techniques, molecular/cell biology (including CRISPR/Cas9), biochemistry, pharmacology, bulk and single cell RNA-sequencing techniques, transgenic and surgically induced animal models, and animal behavioral testing.
Below are recent examples of our work. Please visit our lab website at https://www.sas.rutgers.edu/cms/cbn/peng-jiang-lab/37-peng-jiang-research/340-research-goals for additional information.
· Jiang P, Turkalj L, Xu R. High-Fidelity Modeling of Human Microglia with Pluripotent Stem Cells. Cell Stem Cell. 2020 May 7;26(5):629-631.
· Xu R, Li X, Boreland A, Posyton A, Kwan K, Hart R, Jiang P. Human iPSC-derived mature microglia retain their identity and functionally integrate in the chimeric mouse brain. Nature Communications. 2020 Mar 27;11(1):1577.
· Xu, R., Brawner, A., Li, S., Liu, JJ., Kim, H., Xue, H., Pang, Z., Kim. WY., Hart, R., Liu, Y., Jiang, P. (2019). OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome. Cell Stem Cell. 2019 Jun 6;24(6):908-926.e8.
· Kim, H., Xu, R., Padmashri, R., Dunaevsky, A., Liu, Y., Dreyfus, C., Jiang, P. (2019). Pluripotent Stem Cell-derived Cerebral Organoids Reveal Human Oligodendrogenesis with Dorsal and Ventral Origins. Stem Cell Reports. 2019 May 14;12(5):890-905.
A Ph.D. in neuroscience, stem cell biology or related fields is required. Candidates who have experience with patch-clamp recordings and or CRISPR/Cas9-mediated genome editing in human pluripotent stem cells are desired. Candidates are expected to have strong problem solving, oral and written communication skills, excellent interpersonal skills, and the ability to work effectively and collegially with colleagues in a laboratory setting, as well as independently.
Posting Number 21FA0764
Posting Open Date
Posting Close Date

Minimum Education and Experience
A Ph.D. in neuroscience, stem cell biology or related fields is required.
Required Knowledge, Skills, and Abilities
Equipment Utilized
Physical Demands and Work Environment

Special Instructions to Applicants
Quick Link to Posting https://jobs.rutgers.edu/postings/135704
Campus Rutgers University-New Brunswick
Home Location Campus Busch (RU-New Brunswick)
Location Details

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