Purpose: A postdoctoral position is immediately available in the laboratory of Dr. Xiao Chen in the Division of Hematology and Oncology, Department of Medicine at the Medical College of Wisconsin. The research in the lab focuses on transplantation immunology with a specific emphasis on the immunobiology of graft-versus-host disease (GVHD) and the graft-versus-tumor (GVT) response in mouse models. We are particularly interested in how mucosal immunity is dysregulated during intestinal GVHD. Ongoing research uses genetic, nutritional, and pharmacologic approaches to examine how to target nuclear receptors, including retinoic acid receptor and vitamin D receptor, to prevent and/or treat intestinal GVHD without compromising the GVT response. Highly motivated individuals with a recent Ph.D. and a strong track record of research accomplishments as evidenced by publications in peer reviewed journals are encouraged to apply. Individuals with a strong background in mucosal immunology, tumor immunology, or cancer cellular immunotherapy are particularly encouraged to apply.
Characteristics of a postdoctoral appointment:
It is expected that postdocs at MCW, with the assistance of their supervisor, will:
- Transition to career independence through the development of professional skills that enable the postdoc to actively pursue a career of his/her own choosing.
- Be supervised by at least one senior scholar who actively promotes the postdoc's professional development.
- Establish an individual development plan (IDP) that incorporates equally the postdoc's career and training goals and the mentor's research goals.
- Pursue basic, clinical, or translational projects so long as effort is focused primarily on research.
- Publish results of the postdoc's research and scholarship during their appointment.
- The postdoctoral appointment is temporary by nature, the aggregate amount of time spent as a postdoc is recommended to not exceed five years (not including family medical leave or maternity/paternity leave).
- As postdocs are important members of the host institution's community, appropriate levels of compensation, health care, and other benefits commensurate with their essential status should be afforded, independent of the postdoc's source of funding.
- Plan, design and execute complex research studies, procedures and protocols pertaining to transplantation immunology with a specific emphasis on the immunobiology of graft-versus-host disease (GVHD) and the graft-versus-leukemia (GVL) response in mouse models.
- Participate in discovery projects. Collaborate with principle investigators in determining study design.
- Coordinate research study activities; lead and manage projects.
- Organize, analyze, and interpret scientific data.
- Prepare scientific reports, outcome findings and scientific manuscripts.
- Participate in meetings with principle investigator and research staff in which you will evaluate/interpret the validity of data, develop methodologies, and design and evaluate lab procedures.
- Maintain supplies, may require negotiation with vendors, and track purchase orders.
- May oversee the work of laboratory personnel including training and development as well as daily work direction, delegation and establishing priorities.
- Assist in training students and more junior member of the laboratory. Perform other duties as assigned.
Knowledge – Skills – Abilities
Required knowledge: biology, chemistry, mathematics, statistics, documentation, records management, data utilization, complex problem solving, critical thinking, resource management, and writing skills
Skills and abilities:
- Must be adept at designing and performing experiments and interpreting data.
- Excellent communication skills
Building: MACC Fund Research Center, 6002
Division: Hematology and Oncology
Reports to (Title): Principal Investigator – Dr. Xiao Chen
Collaborates with (Titles): Research staff and students
Full-time role with expectations for coverage during core business hours and flexibility required as necessary to accommodate business needs.
Minimum Required Education: PhD
Preferred Education: PhD in Immunology, Cancer Biology or related field preferred
Minimum Required Experience: No experience required.
Preferred Experience: Transplantation immunology, tumor immunology, or mucosal immunology. Extensive experience with mouse models, flow cytometry, and standard molecular biology techniques
Diversity and Inclusion
The Medical College of Wisconsin defines diversity as a commitment to recognizing and appreciating the variety of individual differences in an environment that promotes and celebrates individual and collective achievement. The diversity of MCW continues to be an important source of innovative ideas and creative accomplishments.
MCW as an Equal Opportunity Employer and Commitment to Non-Discrimination
The Medical College of Wisconsin (MCW) is an Equal Opportunity Employer. We are committed to fostering a diverse community of outstanding faculty, staff, and students, as well as ensuring equal educational opportunity, employment, and access to services, programs, and activities, without regard to an individual's race, color, national origin, religion, age, disability, sex, gender identity/expression, sexual orientation, marital status, pregnancy, predisposing genetic characteristic, or military status. Employees, students, applicants or other members of the MCW community (including but not limited to vendors, visitors, and guests) may not be subjected to harassment that is prohibited by law or treated adversely or retaliated against based upon a protected characteristic.