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Postdoctoral Research Associate - Emergency Medicine - 52066
University of Washington in Seattle, Washington
 
 
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Date Posted 05/22/2021
Category
Admin-Laboratory and Research
Employment Type FullTime
Application Deadline Open until filled
 
 
 
 
 

Post Doc Instructions

Please do not submit an application to this posting.  To apply for this postdoctoral research opportunity, follow the directions below in “Applicant Special Instructions”.



Department Name/Job Location

This position is in the Department of Emergency Medicine.  This position is for the Medical School Campus.



Essential Functions

POSITION SUMMARY:

The Mudd Lab is seeking a post-doctoral research associate to work on the characterization of influenza- and SARS-CoV-2-specific T cells in the lung and draining lymph node of human subjects that have been recently infected with or vaccinated against these important viral respiratory pathogens. The laboratory has recently completed an analysis of antigen specific T cell responses during acute influenza infection [Turner et al. J Infect Dis. 2020. 222(7):1235-44.] and we have now expanded our prospective observational human cohort studies to include sampling of unique physiologic compartments; specifically leveraging already established collaborative teams on campus to sample human lymph nodes using ultrasound-guided fine needle aspiration and bronchoscopy with endobronchial biopsy and bronchoalveolar lavage to sample human lower airways.  The researcher will have the opportunity to work closely with the principal investigator and his collaborator, Dr. Ali Ellebedy [Turner et al. 2020. Nature. 586(7827):127-32.] on several related areas of investigation that are ongoing in both laboratories.  The Mudd and Ellebedy laboratories hold joint weekly laboratory meetings and the associate will be expected to actively participate in scientific discussions related to all ongoing projects in both laboratories while maintaining their own independent projects in the Mudd laboratory.  The researcher's work will involve extensive use of laboratory resources including a 10x Genomics Chromium Controller and a Cytek Aurora spectral flow cytometer.  The candidate will be expected to develop increasingly independent lines of investigation during their tenure. 

In addition to the high-quality research facilities available at Washington University and in the PI’s laboratory environment, the associate will have access to career and professional development training for postdoctoral researchers provided through the Career Center, Teaching Center, Office of Postdoctoral Affairs and other on campus groups.  Additional information on being a postdoc at Washington University in St. Louis can be found at postdoc.wustl.edu/prospective-postdocs .

PRIMARY DUTIES AND RESPONSIBILITIES:

  • Manages their own project, which should lead to a first author publication.
  • Develops expertise in human tissue-resident T cell responses to viral respiratory illness.
  • Develops technical expertise in single-cell transcriptomics and ATAC-seq, complex multi-parameter spectral flow cytometry, as well as high-dimensional data analysis of the resultant datasets.
  • Develops proficiency in career skills, including writing, public speaking, networking and critical evaluation of the scientific literature.
  • Presents scientific work both inside and outside the University with excellent oral communication skills.
  • Assists with grant preparation and reporting.
  • Prepares and submits papers on research with excellent writing skills.
  • Designs research experiments.
  • Evaluates research findings and reports results.
  • Maintains conscientious discharge of their research responsibilities.
  • Maintains conformity with ethical standards in research.
  • Maintains compliance with good laboratory practice, including the maintenance of adequate research records.
  • Engages in open and timely discussion with their mentor regarding possession or distribution of material, reagents, or records belonging to their laboratory and any proposed disclosure of findings or techniques privately or in publications.
  • Maintains collegial conduct towards co-trainees, staff members and members of the research group.
  • Adheres to all applicable University policies, procedures and regulations.  All data, research records and materials and other intellectual property generated in University laboratories remain the property of the University.


  • Required Qualifications

    Ph.D., M.D. or an equivalent terminal or doctoral degree.



    Salary Range

    Base pay commensurate with experience.



    Pre-Employment Screening

    All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. Current employees applying for a new position within the university may be subject to this requirement. The screenings will include a criminal background check and, as applicable for the position, other background checks, drug screen, employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.



    Benefits

    This position is eligible for full-time benefits.  Please click the following link to view a summary of benefits:  https://hr.wustl.edu/benefits/ .



    Applicant Special Instructions

    Interested candidates should forward a letter of interest and a recent Curriculum Vitae to Dr. Philip Mudd, Department of Emergency Medicine, pmudd@wustl.edu .

    WORKING CONDITIONS:

    This position works in a laboratory environment with potential exposure to biological and chemical hazards.  The individual must be physically able to wear protective equipment.



    EOE Statement

    Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.


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