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Postdoctoral Research Associate (IBD) - Gastroenterology - 52061
University of Washington in Seattle, Washington
 
 
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Date Posted 05/20/2021
Category
Admin-Laboratory and Research
Employment Type FullTime
Application Deadline Open until filled
 
 
 
 
 

Post Doc Instructions

Please do not submit an application to this posting.  To apply for this postdoctoral research opportunity, follow the directions below in “Applicant Special Instructions”.



Department Name/Job Location

This position is in the Department of Internal Medicine, Division of Gastroenterology.  This position is for the Medical School Campus.



Essential Functions

POSITION SUMMARY:

THE POSITION: The Ciorba Lab (Gastroenterology) is focused on Intestinal Health and Epithelial Biology. We are now seeking a postdoctoral researcher to join our team’s exciting and mission driven research program. It is anticipated that the initial project of successful candidate will focus on defining mechanisms of intestinal COVID-19 and its interactions with IBD using a novel mouse models and human organoids. This will be in collaboration with expert virologist, thus expertise in virology is not a pre-requisite. Further opportunities are available to develop an independent career development project.

THE LAB: We are a diverse, team-oriented, basic-translational lab researching mechanisms and pathways of intestinal disease. Ultimately, our goal is to leverage this understanding to identify novel therapeutic approaches that will address the unmet needs of patients affected by inflammatory bowel disease (IBD: Crohn’s disease, ulcerative colitis), as well as colon cancer. A major investigational focus is on the intestinal epithelium and intestinal stem cell function during cycles of injury and repair. To achieve this we used modern molecular biology tools, animal models (mice), human tissues, and intestinal organoids (mouse and human derived). We were among the first labs in the world to demonstrate that SARS-CoV-2 could infect human intestinal epithelial cells.

THE SCIENTIFIC ENVIRONMENT: The postdoctoral researcher will have the opportunity to work with welcoming collaborators across the GI division, the School of Medicine and across the US to develop this project and their own independent project.  The GI division has an NIDDK funded Digestive Diseases Research Center (https://ddrcc.wustl.edu/ ) with numerous resources for investigation and funding.  In addition to high-quality research facilities,career and professional development training for postdoctoral researchers is provided through the Career Center, Teaching Center, Office of Postdoctoral Affairs, and campus groups.

 

Additional information on being a postdoc at Washington University in St. Louis can be found at postdoc.wustl.edu/prospectivepostdoc s .

PRIMARY DUTIES AND RESPONSIBILITIES:

Trains under the supervision of a faculty mentor, including (but not limited to):

  • Manages their own project, which should lead to a first author publication.
  • Develops expertise in intestinal inflammation and stem cell biology.
  • Develops proficiency in career skills, including writing, public speaking, networking, and critical evaluation of scientific literature.
  • Presents scientific work both inside and outside the University with excellent oral communication skills.
  • Assists with grant preparation and reporting.
  • Designs research experiments, evaluates findings, and reports results in high quality research papers.
  • Maintains conscientious discharge of their research responsibilities and conformity with ethical standards in research.
  • Maintains compliance with good laboratory practice including the maintenance of adequate research records.
  • Engages in open and timely discussion with their mentor regarding possession or distribution of material, reagents, or records belonging to their laboratory and any proposed disclosure of findings or techniques privately or in publications.
  • Maintains collegial conduct towards co-trainees, staff members and members of the research group.
  • Adheres to all applicable University policies, procedures and regulations.  All data, research records and materials and other intellectual property generated in University laboratories remain the property of the University.
  • Performs other duties as assigned


  • Required Qualifications

    • Doctorate degree (M.D., Ph.D., or equivalent).
    • Experience with techniques in molecular and cellular biology, as well as basic cell culture.
    • Knowledge of basic mucosal immunology/pathobiology.
    • Comfortable with the concept of using vertebrate animal models and is willing to learn mouse models of GI disease.
    • Background in gastrointestinal research and/or a closely related field in epithelial/mucosal disease.
    • Strong oral and written communication skills.
    • Ability to perform the work described and wear protective equipment when necessary.
    • Outstanding documentation and organized record-keeping skills.
    • Experienced with and motivated to improve in experimental troubleshooting, as well as critical, analytical, and creative thinking.


    Salary Range

    Base pay commensurate with experience.



    Pre-Employment Screening

    All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. Current employees applying for a new position within the university may be subject to this requirement. The screenings will include a criminal background check and, as applicable for the position, other background checks, drug screen, employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.



    Benefits

    This position is eligible for full-time benefits.  Please click the following link to view a summary of benefits:  https://hr.wustl.edu/benefits/ .



    Applicant Special Instructions

    Please send a C.V., cover letter, and list of three references with contact information to Dr. Matthew Ciorba at ibd@wustl.edu .  Use subject line “Post Doc”.



    EOE Statement

    Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.


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