Working at MIT offers opportunities, an environment, a culture – and benefits – that just aren’t found together anywhere else. If you’re curious, motivated, want to be part of a unique community, and help shape the future – then take a look at this opportunity.
POSTDOCTORAL ASSOCIATE, IMMUNOLOGY Biological Engineering-Synthetic Biology Center , to pursue research on the synthetic immune system for COVID-19, West Nile Virus, H1N1, and emerging viral infections. Will work with a team of researchers, principal investigators (PIs), and lab manager to participate in government and corporate-sponsored research programs in the area of mammalian synthetic immune systems. Synthetic immune systems are created from mammalian genetic circuits that will sense cell state, including mRNA, miRNA, metabolites, viral entry, etc., and implement functions that result in precise responses such as transcription factors antiviral therapy. Responsibilities will include designing sophisticated genetic circuits (e.g., use of CRISPR/Cas9, molecular cloning, mammalian cell culture, DNA transfection, lentiviral transduction); designing assays; collecting data using state-of-the-art techniques, including flow cytometry, RT-qPCR, next-generation sequencing, ELISA, and other analytic technologies; working with cross-functional teams for microfluidic and high-throughput scale-up; data analysis, including computational skills; communicating results--verbally and in writing--to team members (including scientists from sponsoring firm or government agencies); making presentations to the scientific community through talks and publications; and performing other tasks as needed.
REQUIRED: Ph.D. in biological sciences, computer science, engineering, physics, math, or related field; experience in at least one of the following—immunology, mammalian cell culture, large scale DNA assembly and characterization, genetic recombination technology, next-generation sequencing, computational methods and tools for analysis, and statistics; biological experience with molecular biology, protein engineering, immunology, and/or cell biology; ability to prioritize, perform multiple tasks, and execute detailed technical protocols meticulously; strong organizational, analytical, problem-solving, and documentation skills; and ability to work collaboratively and on individual projects in a dynamic, multidisciplinary, team-oriented setting. Job #19608