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Life Science Research Professional 1 – Mackall Lab
Stanford University in Stanford, California
 
 
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Date Posted 05/13/2021
Category
Admin-Laboratory and Research
Employment Type
Application Deadline Open until filled
 
 
 
 
 

Life Science Research Professional 1 – Mackall Lab

The Mackall lab seeks to discover fundamental principles that control tumor and immune interactions and to apply these insights to develop novel immunotherapies for cancer.  Current areas of major focus include in depth studies of the molecular and cellular processes that govern T cell exhaustion, identification of new immune targets expressed by cancer and leveraging emerging synthetic biology platforms to create next generation chimeric antigen receptors that manifest enhanced potency, regulatability, multispecificity and exhaustion resistance. We are a multidisciplinary team, which spans undergraduate researchers, graduate students and postdoctoral fellows, medical students and physicians and early career and senior scientists with expertise in cellular immunology, molecular immunology and oncology, synthetic biology, computational science and clinical investigation.  The Mackall laboratory works closely with clinical and translational investigators within the Stanford Center for Cancer Cell Therapy to test novel therapeutics in early phase clinical trials and to identify biomarkers of response and mechanisms of resistance to cancer immunotherapies.

The Stanford Cancer Institute (SCI) is one of an elite number of National Cancer Institute-Designated Comprehensive Cancer Centers in the country, and is a prominent, dynamic, growing and complex Institute within the Stanford University School of Medicine.  The SCI actively works to build synergies and collaborations among faculty with cancer-relevant expertise from four Schools and over 30 departments across Stanford University.  We seek a LSRP1 to help us enact our mission to reduce cancer mortality through comprehensive programs of cancer research, treatment, education and outreach.  Given the SCI’s mission, breadth, and depth, it employs over 325 staff members in a fast-paced, team-oriented, and forward-thinking environment with tremendous opportunities for personal and professional growth.  You will be working with an unparalleled leading edge community of faculty and staff who are fundamentally changing the world of health care in the cancer arena.

Reporting to a Senior Research Scientist, the LSRP1 will be conversant in the goals, mission and priorities of the Institute.   We are seeking candidates with excellent organizational and communication skills.  Our staff run toward challenges, and you will have a demonstrated history of doing the same with a high degree of professionalism, initiativeand flexibility. 

Duties include:

  • Plan and perform experiments in support of research projects in lab and/or field based on knowledge of scientific theory. Interpret and perform basic analyses of results.
  • Review literature on an ongoing basis to remain current with new procedures and related research.
  • Offer suggestions regarding modifications to procedures and protocols in collaboration with graduate post-doctoral individuals.
  • Maintain detailed records of experiments and outcomes.
  • Contribute to publication of findings as needed. Participate in the preparation of written documents, including procedures, presentations, and proposals.
  • Help with general lab maintenance as needed; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed.
  • Help orient and train new staff or students

*- Other duties may also be assigned


DESIRED QUALIFICATIONS:

Desired candidate should have experience in sterile technique and cell culture, basic molecular biology techniques including cloning. He/she should have experience in T cell transduction, production of viral supernatants, ELISA, and multicolor flow cytometry. Experience in handling mice for in vivo experimentation and processing murine samples is highly desired.  A bachelor’s degree in cell biology or molecular biology is preferred.

EDUCATION & EXPERIENCE (REQUIRED):

Bachelor's degree in related scientific field.

KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):

  • General understanding of scientific principles. Demonstrated performance to use knowledge and skills when needed.
  • Demonstrated ability to apply theoretical knowledge of science principals to problem solve work.
  • Ability to maintain detailed records of experiments and outcomes.
  • General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
  • Ability to work under deadlines with general guidance.
  • Excellent organizational skills and demonstrated ability to accurately complete detailed work.

CERTIFICATIONS & LICENSES:

None

PHYSICAL REQUIREMENTS*:

  • Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.
  • Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
  • Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.
  • Must have correctible vision to perform duties of the job.
  • Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
  • Ability to lift heavy objects weighing up to 50 pounds.
  • Ability to work in a dusty, dirty, and odorous environment.
  • Position may require repetitive motion

*- Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.

WORKING CONDITIONS:

  • May require working in close proximity to blood borne pathogens.
  • May require work in an environment where animals are used for teaching and research.
  • Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
  • Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.
  • May require extended or unusual work hours based on research requirements and business needs.

WORK STANDARDS:

  • Interpersonal Skills: Demonstrates the ability to work well with Stanford colleagues and clients and with external organizations.
  • Promote Culture of Safety: Demonstrates commitment to personal responsibility and value for safety; communicates safety concerns; uses and promotes safe behaviors bases on training and lessons learned.
  • Subject to and expected to comply with all applicable University policies and procedures, including but not limited to the personnel policies and other policies found in the University’s Administrative Guide, http://adminguide.stanford.edu.

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