Post-Doctoral Researcher, Biology
Job no: 495875
Work type: Full-Time
Location: University City - Philadelphia, PA
Categories: College of Arts & Sciences, Drexel University
Drexel is a comprehensive global research university ranked among the top 100 in the nation. With over 24,000 students, Drexel is one of America's 15 largest private universities. Drexel is one of Philadelphia's top 10 private employers, and a major engine for economic development in the region. Drexel has committed to being the nation’s most civically engaged university, with community partnerships integrated into every aspect of service and academics.
A Post-Doctoral position is available immediately in the Biology Department of the College of Arts and Sciences. The position is funded by an NIH grant, to study how signaling pathways that sense endoplasmic reticulum stress are integrated during cell differentiation and under pathological conditions such as neurological disease. More specifically, this is a joint project between the Gidalevitz lab at Drexel and the Argon lab at CHOP. The goal is to explore, using genetic and cell biological models, how the dynamics of the IRE1/XBP1 and PERK/eIF2a pathways change during sensory neuronal development and neurodegeneration (Klabonski et al., PLoS Gen. 2016), or differentiation of antibody (Gaudette et al., Nature Comm. 2020) or insulin-secreting cells (Eletto, D., et al. FASEB J, 2016), and how they are modulated by proteostatic stress conditions. Future projects in the lab will use screenings of chemical libraries and forward and reverse genetics in cell culture, mouse, and C. elegans models. Energetic applicants with strong experimental background in biochemistry, molecular and cellular biology and/or genetics are encouraged to apply. Experience with primary neuronal cultures is a plus.
- Study how signaling pathways that sense endoplasmic reticulum stress are integrated during cell differentiation and under pathological conditions such as neurological disease.
- Conduct projects in the lab using screenings of chemical libraries and forward and reverse genetics in cell culture, mouse, and C. elegans models.
- Work independently in executing experiments and analyzing data, as well as being organized and maintaining an up-to-date notebook that details all experimentation.
- Other related duties as assigned.
- PhD or Doctorate in Biology or another STEM field
- 5 years of relevant experience in biochemistry, molecular and cellular biology, and/or genetics
- Strong organizational and communications skills
- Strong experimental background in biochemistry, molecular and cellular biology and/or genetics.
- Experience with primary neuronal cultures
- Typically standing at a desk/table
- Typically standing, walking
This position is classified as Exempt with a salary grade of I. For more information regarding Drexel’s Professional Staff salary structure, https://drexel.edu/hr/career/ducomp/salstructure/
Special Instructions to the Applicant
Please make sure you upload your CV/resume, cover letter, and references when submitting your application.
Review of applicants will continue until a suitable candidate pool is identified.
Advertised: May 7 2021 Eastern Daylight Time
Applications close: Jun 7 2021 Eastern Daylight Time
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