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Postdoctoral Research Scientist
Columbia University in New York City, New York
Date Posted 02/25/2021
Admin-Laboratory and Research
Employment Type
Application Deadline Open until filled

Posting Details

Job Requisition Number 00002246
Field(s) of Specialization Neuroinflammation
Position Title Postdoctoral Research Scientist
Department SRG Surgery
Division Surgery
Location Medical Center
Summary Description

The Division of Surgical Science in the Department of Surgery at Columbia University Vagelos College of Physicians and Surgeons is accepting applications for a Postdoctoral Research Scientist. Individual will be responsible for performance and development of a research project that focuses on cellular and molecular mechanism underlying neuroinflammation and innate immune response relevant to basic and translational study in novel transgenic mouse model. The recruitment will focus on the study of proinflammatory mediators, innate immune response, monocytes/macrophage and microglial function, neurodegeneration in primary neurons and in brain of in vivo animal model.

Minimum Degree Required

PhD, MD or MD/PhD

Minimum Qualifications

Experience in Biological Sciences, at least two-year research experience in neurophysiology and electrophysiology and/or cell biology in vitro and in vivo. Strong skills in major biochemistry and cell biology techniques, animal handling, brain injection, primary cultures and quantitative data analysis related to neurophysiology are also required. Candidate must have the ability to work independently after a short training period and have at least 2-3 publication s related to neurophysiology or synaptic degeneration and synaptic transmission.

Preferred Qualifications
Additional Information

Responsibilities of the individual will include:
1) Perform of laboratory research in the area of neuroinflammation, inflamed cells and microglia, flow cytometer for determining different types cells involved in inflammation, and neurodegeneration.
2) Analysis of monocyte, macrophage, and microglial profile with specific cell surface markers by immunostaining, cell sorting, and flow cytometery, and single RNA sequence in primary and continuous cell lines, viral transfections in vitro and in vivo.
3) Perform primary mouse neuronal culture, immunostaining/fluorescence and confocal microscopy neuroanatomy and neuropathology in vitro cultured neurons and in vivo brain section or isolation of infiltrated cells from brain or blood.
4) Perform plasmid DNA preparation, immunoblotting and RNA analysis for protein expression and pattern and gene changes.
5) Perform literature searches, manage data, analyze experimental results and published data. Participate to the development of an extramurally funded research program by assisting PIs with NIH grants.by developing and generating data and figures

RAPS posting date 02/24/2021
Search Closing Date
Special Instructions to the Applicant
Proposed Start Date 04/01/2021
EEO Statement

Columbia University is an Equal Opportunity Employer / Disability / Veteran

Review Begins 02/24/2021
Quick Link https://pa334.peopleadmin.com/postings/7175

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