Scientist, In Vivo Pharmacology
Job Description
Who We Are:At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs, but few options.
What We Do:Neurocrine Biosciences is a neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs, but few options. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, endocrine and psychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, Parkinson's disease, endometriosis* and uterine fibroids*, as well as clinical programs in multiple therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. *in collaboration with AbbVie
About the Role:
As part of the In Vivo Biology team, this individual would be a key contributor in the development of novel therapeutics in the neurology and neurodegenerative space. The role would encompass primarily in vivo and some ex vivo analysis of novel drug targets and screening of potential therapeutic compounds (AAV, small molecules, antibodies and peptide compounds), study design, execution of procedures and data analysis in a team setting. The candidate is expected to independently design and perform studies while also working collaboratively with colleagues in multiple departments across the R&D organization to support the development of novel therapeutics. The role requires a breadth of laboratory experience across in vivo model systems from logistical consideration to study execution and analysis. Prior experience with transgenic mouse models and a deep understanding of animal behavior is highly desired._
Your Contribution (include, but are not limited to):Performs assigned experiments to support scientific activities and project goals
Recommends alternatives, researches new methods and techniques and may proactively seek out senior personnel to discuss potential solutions to problems
Tissue dissection (multiple brain regions, spinal cord, liver, heart, muscle)
Dosing via multiple routes of administration (PO, SC, IP, IV, RO, ICV)
Responsible for behavioral assay development, validation, and screening
Completes data analysis and reporting. Maintains and updates SOP's and writes data summaries for experiments conducted
Reviews, comprehends and complies with all SOP's, IACUC procedures, and safety and quality assurance standards at all times
Coordinates outside testing with CROs, maintains contracts and communication with outside vendors
Provides training and/or supervision to junior staff, as needed
Other duties as assigned
BS/BA degree in biological sciences preferably related to behavioral neuroscience, pharmacology or biopsychology and 2+ years of experience in the handling and dosing of rodents in a laboratory setting OR
MS/MA degree in biological sciences preferably related to behavioral neuroscience, pharmacology or biopsychology and some relevant experience preferred OR
PhD degree in biological sciences preferably related to behavioral neuroscience, pharmacology or biopsychology and some relevant experience preferred
Extensive hands-on knowledge of behavioral testing in a variety of assays
Occasional weekend work required
Recognizes fundamental anomalies in data points and identifies issues in experiments/processes
Begins to understand how to think outside of the technical process and consider the impact decisions will have on the broader scientific goals
Strong knowledge of experimental design and behavioral phenotyping
Strong knowledge of mouse models of neurodegeneration
Good knowledge of scientific principles, methods and techniques
Good knowledge and demonstrated ability working with a variety of laboratory equipment/tools
Strong computer skills
Good communications, problem-solving, analytical thinking skills
Ability to meet deadlines
Good project management skills
High level of organization and attention to detail
Willingness and ability to work both independently and as part of a team
Must have working knowledge of Microsoft Office, Word, and Excel
Advanced multitasking, trouble shooting and deductive reasoning skills required
#LI-OB1
Neurocrine Biosciences is an EEO/AA/Disability/Vets employer.
We are committed to building a diverse, equitable, and inclusive workplace, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don't line up to exactly what we have outlined in the job description.
_
The annual base salary we reasonably expect to pay is $86,200.00-$125,050.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 20% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.
*Please mention you saw this ad on AcademicJobs.*
