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POSITION TITLE: Postdoctoral Associate

POSITION SUMMARY:

The Jardine Laboratory at Scripps Research is seeking applications for a Postdoctoral Associate to help drive our antibody discovery and engineering efforts. We are an interdisciplinary lab that utilizes an engineering approach to study biological problems and design potential interventions. We specialize in structure-based protein engineering and use a combination of high throughput platforms paired with conventional cell sorting and deep sequencing. Many of our projects span multiple labs here at Scripps that have complementary skillsets and/or relevant biological models. We also work close with Calibr, the translational division at Scripps Research focused on therapeutic development. Our current efforts include working on antibodies for HIV, malaria, and snake bite envenoming as well as to understand (and potentially treat) autoimmunity and immune modulators.

• Conduct antibody discovery campaigns using synthetic libraries and/or single B cell sorting.
• Produce and characterize antibodies from discovery campaigns.
• Measuring binding affinity (e.g. ELISA, SPR, cell surface staining, etc).
• Evaluate biochemical behavior (polyreactivity, SEC, TM, etc)
• Establish relevant functional screening assay for target antigen (e.g. neutralization assay or cytokine release assay) and evaluation of candidate antibodies to identify lead candidates.
• Conduct data analysis and interpretation and use solution-oriented, creative thinking to address technical hurdles.
• Draft manuscripts for research publication and present findings at major scientific conferences.

Postdoctoral Associates are appointed positions for the purpose of developing scholarly competence, working under the supervision of a Scripps Research Faculty member. These appointments are normally not renewed beyond a total of five years. Postdoctoral Associates cannot apply for external funding either as a Principal Investigator or Co-Principal Investigator without prior approval from a Departmental Chair. Postdoctoral Associates do not have consulting privileges.

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REQUIREMENTS:

• PhD in a relevant field with a strong publication record is required. A pending doctoral degree may be considered with approval of the Principal Investigator.
• Excellent analytical, problem-solving, and communication skills.
• Ability to work collaboratively in a dynamic, interdisciplinary research environment.
• Excellent communication skills, including writing reports and manuscripts and delivering engaging presentations is required.
• Good interpersonal skills with cultural sensitivity and respect for diverse colleagues is required.

COMPENSATION: Postdoctoral Associates will be hired following the National Institute of Health and California's exempt salary guidelines, which provide for a starting range of $68,000- $73,230. Consideration will be given to experience that exceeds the listed requirements.

COMPREHENSIVE BENEFITS INCLUDE:

• Eligibility for retirement plans with employer contribution.
• Full suite of Health and Welfare plans including three medical plan options (including an HSA available option), dental, vision, life insurance, disability, EAP and more.
• Access to Flexible Spending Accounts (Medical/Dependent Care).
• Competitive vacation and sick leave policies.
• Free, on-site Counseling Center which provides confidential counseling services to benefits-eligible employees and their family members.
• Free, on-site parking.
• Pet insurance

The above statements describe the level of work performed and expected in general terms. The statements are not intended to list all the responsibilities, duties and/or skills required of employees so classified, and the content herein is subject to change due to the business needs of Scripps Research, with or without notice. Furthermore, nothing in this job description shall be interpreted to be in conflict with or to eliminate or modify in any way the employment-at-will status of Scripps Research staff.

EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. We promote diversity of thought, culture and background in the fields of science. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status. Underrepresented individuals are encouraged to apply.