389369BR

USA

About the role

Position is onsite in San Diego
#LI-Onsite
Novartis Biologics Research Center (BRC) is a leader at the cutting edge of innovative medicine development to improve patient lives. BRC builds the biologics pipeline in collaboration with Novartis Biomedical Research (NBR) Disease Areas and Platforms via a breadth of technologies for discovery of antibody, protein, gene therapy and RNA-based therapeutics.
We are seeking a highly motivated scientist to contribute to gene therapy development as part of the global community of investigators in the Cell & Gene Therapy (CGT) group within BRC. The successful candidate will work at the cutting edge of gene therapy biodistribution, platform and technology research to model and test priorities in translational research. The successful candidate will be a collaborative scientist experienced in molecular biology experiments, liquid handling automation and/or NGS sequencing.
Key responsibilities:
*Lead in vivo biodistribution and platform analysis projects as part of internal CGT programs
*Implement molecular and cellular biology assays to analyze in vitro and in vivo samples for viral vector based gene therapy characterization with techniques such as PCR/qPCR/dPCR, IF/IHC, and/or ELISA/MSD
*Develop molecular biology assays for the specific needs of internal CGT programs
*Implement liquid handling & automation protocols as part of experiments to increase analysis capabilities and throughput and/or operate next-generation sequencing (NGS) platform instrumentation (Illumina, PacBio, etc.) and analyze data from targeted experiments
*Research, develop and onboard new and emerging techniques and technologies for in vivo CGT analysis
*Use current and new technologies to contribute to CGT platform development
*Prepare quality data sets and reports adhering to the good research practices and quality culture across BRC
*Present results at appropriate internal and external meetings and conferences
*Multiple positions available.

EEO Statement

We are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Accessibility and Reasonable Accommodations: Individuals in need of a reasonable accommodation due to a medical condition or disability for any part of the application process, or to perform the essential functions of a position, please let us know the nature of your request, your contact information and the job requisition number in your message:

• Novartis: e-mail us.reasonableaccommodations@novartis.com or call +1 (877)395-2339
  
• Sandoz: e-mail reasonable.accommodations@sandoz.com or call: +1-609-422-4098

Role Requirements

*Scientific background with an BS in Biological Sciences or a closely related discipline with 1+ years of academic or industry lab related experience. Industry experience is preferred. Masters preferred.
*This lab-based position is located in San Diego, CA and will not have the ability to be located remotely
*Experience with molecular and cellular biology techniques (such as digital PCR, ELISA, IF/IHC NGS, nucleic acid extraction, qPCR, and/or transcriptomics) is required
*Willingness to independently pursue assay and technological development of molecular biology techniques to advance gene therapy
*The position requires the ability to work collaboratively in a dynamic team centric scientific environment and adaptability to emerging project/group needs, excellent communication and presentation skills, both written and verbal, and strong interpersonal skills
Desirable Requirements:
*Experience with liquid handling automation and writing related protocols using programming language is highly desired
*Experience with operating next-generation sequencing (NGS) platform instrumentation (Illumina, PacBio, etc.) and analysis of short-read and long-read sequencing data is also desired
*Experience with Hamilton Venus software is preferred
*Experience with laser capture microscopy, single cell genomics and/or spatial genomics also preferred
*Experience in animal models, viral vector based gene therapy and delivery, and molecular virology are highly desired
Why Novartis:
Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients' lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-cultureBenefits and Rewards: Read our handbook to learn about all the ways we'll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewardsCommitment to Diversity & Inclusion: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.
Novartis Compensation and Benefit Summary:
The pay range for this position at commencement of employment is expected to be between $80,000 and $120,000 /year; however, while salary ranges are effective from 1/1/24 through 12/31/24, fluctuations in the job market may necessitate adjustments to pay ranges during this period. Further, final pay determinations will depend on various factors, including, but not limited to geographical location, experience level, knowledge, skills, and abilities. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an "at-will position" and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team

Division

Biomedical Research

Business Unit

BIOLOGICS RESEARCH CENTER

Work Location

San Diego, CA

Company/Legal Entity

NIBRI

Functional Area

Research & Development

Job Type

Full Time

Employment Type

Regular

Shift Work

No

Early Talent

Yes