About City of Hope

City of Hope is an independent biomedical research and treatment organization for cancer, diabetes, and other life-threatening diseases.

Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope's translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution. AccessHope™, a subsidiary launched in 2019 serves employers and their health care partners by providing access to City of Hope's specialized cancer expertise.

A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation's "Best Hospitals" in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.

City of Hope's commitment to Diversity, Equity, and Inclusion

We believe diversity, equity and inclusion is key in serving our mission to provide compassionate patient care, drive innovative discovery, and advance vital education focused on eliminating cancer and diabetes in all our communities. Our commitment to Diversity, Equity and Inclusion ensures we bring the full range of skills, perspectives, cultural backgrounds, and experiences to our work -- and that our teams align with the people we serve to build trust and understanding. We are dedicated to fostering a community that embraces diversity - in ideas, backgrounds, and perspectives; this is reflected in our work and represented in our people.

Position Summary

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. Steven Rosen, at the Beckman Research Institute of City of Hope, a prestigious NCI-designated Comprehensive Cancer Center.

The candidate will directly work with supervisor and lab members to investigate the effects of inhibition of SUMOylation on cancer progression and anti-tumor immunity. The goal of this position is to reveal mechanisms of therapy resistance and develop novel methods to advance current therapy for myeloma and leukemia.

Skills that are used in the lab include: hands-on lab benchwork on cell biology, immunology, and animal tumor models; design and conduct experiments; generate, analyze and evaluate data present results in an organized manner; learn new techniques and approaches; stay updated with latest advancement in the field and integrate them into research.

Basic education, experience and skills required for consideration:

· PhD degree in Cancer Biology, Molecular Biology, immunology, or related field (required).

· Peer reviewed publications in the area (required).

· Experience with murine tumor model including mice handling, tumor engraftment, drug administration, tissue dissociation (required).

· Strong oral and written communication and organizational skills (required).

· Cell and molecular biology techniques including cell culture, western blot, and qPCR (required).

· Expertise in immunology-related basic techniques such as flow cytometry (highly preferred).

· Experience in computational biology, bioinformatics, transcriptomic, proteomic, data analysis (highly preferred).

Additional Information:

As a condition of employment, City of Hope requires staff to comply with all state and federal vaccination mandates.

· Please include an updated CV, a cover letter describing your current position, reasons for applying and contact details of two referees.

· For more information on Dr. Steven Rosen lab, please visit here: https://www.cityofhope.org/steven-rosen#paragraph-336036

The estimated pay scale represents the typical [salary/hourly] range City of Hope reasonably expects to pay for this position, with offers determined based on several factors which may include, but not be limited to, the candidate's experience, expertise, skills, education, job scope, training, internal equity, geography/market, etc. This pay scale is subject to change from time to time.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.