Details

Posted: 11-Oct-23

Location: Portland, Oregon

Type: Full-time

Salary: Open

Categories:

Academic/Faculty

Internal Number: 26143

Department Overview

The School of Dentistry shares the mission of the Oregon Health & Science University to provide educational programs, basic and clinical research, and high quality care and community programs. We strive to foster an environment of mutual respect where the free exchange of ideas can flourish. The dental school prepares graduates in general dentistry and the dental specialties to deliver compassionate and ethical oro-facial health care.

Read more about the School of Dentistry: OHSU School of Dentistry

Function/Duties of Position

The successful candidate will work independently to investigate the molecular genetic mechanisms supporting polymicrobial pathogenesis in oral dysbiotic diseases. He/she will be responsible for most of the planning, implementation, and data interpretation associated with his/her research. Thus, the candidate will be expected to work independently with attention to detail and strong record-keeping. The goal is to understand how certain dysbiotic communities dysregulate the immune response, especially via the production of gene products that target host genetic pathways or other members of the oral microbiome. To achieve this goal, we are particularly interested to improve the genetic tractability of a variety of understudied species in the oral microbiota. Typical laboratory techniques often require expertise with northern blot, western blot, protein expression/purification, coimmunoprecipitation, gene expression analysis, targeted mutagenesis, microscopy, and bacterial community analysis.

Demonstrable experience with the human microbiome as well as these techniques is preferred. As a postdoctoral scholar, the candidate may also be involved with the training and supervision of students and junior staff as well as play an integral role in the management and supply ordering for the laboratory. Assistance with the development and preparation of grants/manuscripts will also be expected.

Required Qualifications

• Doctorate degree in (genetics, biochemistry/molecular biology, microbiology, immunology, or another relevant field)
• Demonstrable experience with some or all of the following: bacterial genetics, protein chemistry, proteomics, coimmunoprecipitation, EMSA, RNA purification/analysis, gene expression/transcriptomics, bacterial community analysis, cell culture, and FACS
• Grant and/or manuscript preparation experience
• Planning, implementation, and data interpretation experience
• Excellent oral and written communication skills
• Organizational and time management skills that maintain timeliness of work and accurate prioritization
• Ability to train and supervise students and junior staff Attention to detail and strong record keeping experience/skills
• Able to conduct research in a multidisciplinary, fast-paced research environment, occasionally with tight deadlines
• Able to work independently and exhibit self-motivation
• Able to stand at a lab bench, sit at a microscope, perform laboratory manipulations, move and carry light lab equipment, perform image analysis experiments, operate computers and related software, communicate easily with co-workers and support staff, assist and instruct other lab members with scientific methods

Preferred Qualifications

• Doctoral degree and/or postdoctoral research related to bacteriology or immunology

• Experience/knowledge of the microbiome, especially the oral flora

• Experience with oral bacterial genetics and/or oral immunology

All are welcome
Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.