The Center for Drug Discovery ( https://www.bcm.edu/research/centers/drug-discovery ) is a strategic research center at Baylor College of Medicine in Houston, Texas. We are currently seeking highly motivated, well-organized and enthusiastic Postdoctoral Fellows contributing to our research in the fields of drug metabolism and toxicity, as well as the study of chemical properties that aid in crossing the blood-testis barrier (BTB). In our well-equipped laboratory, we utilize advanced instruments such as Thermos UHPLC-Q Exactive MS, Orbitrap Exploris™ 120, Thermo Quintus (triple quadruple), and Imaging mass spectrometry (IMS, Bruker timsTOF fleX MALDI-2) to conduct LC-MS-metabolomics, pharmacokinetics, and spatial metabolomics. Understanding the drug metabolism could predict the possible adverse events of drugs in clinic and also could reduce the risk of the drug candidates in drug development. Determining chemical features passing BTB will facilitate the drug development for therapeutic targets behind BTB. Baylor College of Medicine is located in the prestigious Texas Medical Center and offers a highly interactive environment and a strong infrastructure for research and career development. To obtain further details about the positions, feel free to email Dr. Feng Li (fl3@bcm.edu) directly.

Job Duties

• Plans, designs and conducts experiments.
• Characterizes the drug metabolites using High-resolution LC-MS and NMR.
• Synthesizes the elaborately designed molecules to test tthier ability to pass through BTB.
• Documents and interprets results of experiments and report to principal investigators.
• Conducts literature searches and summarizes information in an appropriate format for a particular study.
• Designs and performs experiments, data analysis.
• Helps to write and prepare manuscripts.

Minimum Qualifications

• MD or Ph.D. in Basic Science, Health Science, or a related field.
• No experience required.

Preferred Qualifications

• Doctoral degree in Organic Chemistry, Drug metabolism and pharmacokinetics, Pharmacology, and Toxicology, or a related Biomedical Science discipline.
• Experience in Organic synthesis and structural characterization using LC-MS and NMR.
• Skilled in the identification of drug metabolites in vitro and in vivo.
• Experience in administrating mouse with drugs.
• Experience in LC-MS method development and sample preparation, and data analysis.

Baylor College of Medicine requires employees to be fully vaccinated -subject to approved exemptions-against vaccine-preventable diseases including, but not limited to, COVID-19 and influenza.

Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.

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