Baylor College of Medicine has an opportunity for a Postdoctoral Research Associate position with a focus on integrative analysis of transcriptomic, epigenomic, metabolomics and proteomic large-scale datasets, under joint supervision of Dr. Cristian Coarfa and Dr. Andrew DiNardo. The position will involve single cell multi-omics analysis and data science to support research aimed at understanding long-term molecular changes associated with tuberculosis with implications in patient level risk assessment and host-directed therapies (Dinardo et al ERJ 2022, Bobak et al Aging 2022).

The position is intended for Computer Science, Computational Biology, or life science graduates transitioning to a data science and bioinformatics career. The successful candidate will receive training in analyses of single-cell and bulk-tissue multi-omics data and be expected to participate in multiple projects involving design, implementation and integration of large-scale datasets and data processing pipelines.

• Analyzes single cell RNA-Sequencing, single cell ATAC-Seq, CITE-Seq, as well as bulk RNA-Seq, Proteomics, Metabolomics, and Lipidomics datasets, generated from tuberculosis patient cohorts with rich clinical data.
• Conducts advanced modeling of post tuberculosis lung disease risk using approaches including generalized linear models and deep learning.

• MD or Ph.D. in Basic Science, Health Science, or a related field.
• No experience required.

• Experience in epigenetics or gene regulation is a plus, and experience with statistical analysis tools such as R or Python is recommended (successful candidates will be expected to pass a basic programming test in Python).
• Excellent written and verbal English skills, strong communication and interpersonal skills, and be capable of working with large collaborative teams.
• Candidates must have a Ph.D. in Computer Science, Bioinformatics, or biology, as well as a strong background in statistics, and familiarity with large data sets such as proteomics or sequencing.

Baylor College of Medicine requires employees to be fully vaccinated -subject to approved exemptions-against vaccine-preventable diseases including, but not limited to, COVID-19 and influenza.

Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.

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PD; CH; SN