Position Description:

Applications are invited for a postdoctoral fellow position in Metabolic Systems Modeling starting immediately in the Laboratory of Dr. Ranjan Dash within the Departments of Biomedical Engineering and Physiology, Medical College of Wisconsin. The fellow will work on an integrated research project combining computational modeling and experimental measurements of cardiac and renal mitochondrial and cellular metabolic functions (e.g. substrate utilization; bioenergetics; cations and ROS homeostasis). The overall goal is to quantitatively characterize the biophysical and biochemical mechanisms associated with cardiac and renal mitochondrial and cellular metabolic dysfunctions and oxidative stress in salt-sensitive hypertension and related pathologies.

The fellow will have the opportunity to participate in wet-lab experiments (e.g. isolated mitochondria, isolated cells, and tissue homogenates from the heart and kidney) in addition to computational modeling and analysis. The research will afford the fellow a significant training and exposure on the mechanistic computational modeling of biological mass transport and exchange processes as well as of integrated metabolic systems in the heart and kidney, which will also provide opportunities for other applications, including in the area of lung tissue bioenergetics and hyperoxia-induced lung injury. The fellow will also gain the training and experience needed to become an independent researcher in the larger field of metabolic research.

Funding for this position is through a NIH-funded R01 grant, which involves close collaboration with Prof. Allen Cowley, Jr. (MPI), Department of Physiology, Medical College of Wisconsin. Dr. Dash also collaborates with many other renowned researchers at the Medical College of Wisconsin, Marquette University, University of Wisconsin-Milwaukee, and other universities and institutions beyond South-East Wisconsin. More about Dr. Dash’s lab and his research and publications can be found at his lab website (https://mcw.marquette.edu/biomedical-engineering/directory/ranjan-dash.php ).

Preferred Schedule:

Position Requirements:

The minimum criteria for the position are enumerated below:

(1)  A Ph.D. degree in bioengineering, biomedical engineering, biochemical engineering, applied mathematics, or a related scientific field. Completion of the Ph.D. dissertation within the last 2 years will be highly desirable.

(2)  A background in cellular metabolism, physiological systems, cardiovascular physiology, mathematical modeling of complex biological systems, experimental data analyses, computational methods, and scientific and technical computing skills using MATLAB. Experience in computer programming using other languages, such as FORTRAN, C, and C++ will be an added advantage.

(3) Good communication skills (written/spoken English) and evidence of successful publication of scientific manuscripts.

(4)  A keen desire and initiative to learn and the ability to function both independently and as a part of a collaborative team.

MCW as an Equal Opportunity Employer and Commitment to Non-Discrimination
The Medical College of Wisconsin (MCW) is an Equal Opportunity Employer. We are committed to fostering a diverse community of outstanding faculty, staff, and students, as well as ensuring equal educational opportunity, employment, and access to services, programs, and activities, without regard to an individual's race, color, national origin, religion, age, disability, sex, gender identity/expression, sexual orientation, marital status, pregnancy, predisposing genetic characteristic, or military status. Employees, students, applicants or other members of the MCW community (including but not limited to vendors, visitors, and guests) may not be subjected to harassment that is prohibited by law or treated adversely or retaliated against based upon a protected characteristic.

.