Cardiovascular Research Inst

Full Time

73926BR

Job Summary

We study how integrins and extracellular matrix molecules regulate tissue regeneration after injury and whole body metabolism. The research spans in vitro genetic screens with cell lines and primary cells through in vivo models of fibrosis with mice and evaluation of human samples. The individual hired will be involved in all aspects of the research including obtaining primary data.

The duties will include, but are not limited to, performing cell and molecular biology experiments, maintaining cell cultures, harvesting primary cells from mice, genotyping mice and maintaining the mouse colony, performing flow cytometry, carrying out in vivo models of fibrosis in mice, ordering reagents and keeping track of lab reagent stocks, as well as participating in the general care and maintenance of equipment.

Staff Research Associate I is the entry level in the series. Incumbents may perform a limited variety of non-standard repetitive procedures or a wide variety of standard repetitive procedures characteristic of the next higher level, but without having reached the level of skill proficiency required at the next higher level. Under supervision, incumbents perform standard repetitive, technical laboratory and/or field experimental procedures and/or receive training in the more difficult procedures usually requiring a theoretical background in one scientific field.

Incumbents usually perform standard repetitive procedures of limited variety and/or work under close technical supervision, in their initial assignments. Originality in devising or revising laboratory and/or field experimental procedures is ordinarily not expected nor required at this level. Continuing supervision over other staff personnel is not normally assigned.

Staff Research Associate II may be assigned the management responsibility for a small laboratory unit, with at least one Staff Research Associate I or a group of lower-level laboratory employees such as Laboratory Assistants, Animal Technicians, etc. This type of responsibility typically includes ordering supplies and equipment and insuring proper operation and maintenance of laboratory equipment. Under supervision, incumbents perform (a) a wide variety of standard repetitive laboratory and/or field experimental procedures at the full operational or journey level of skill in one field of specialty; or (b) perform a limited variety of non-standard laboratory and/ or field experimental procedures requiring ingenuity, resourcefulness, and adaptability to special and changing needs of research in one specialized field; or (c) perform a limited variety or repetitive but highly specialized laboratory and/or field experimental procedures.

Incumbent typically perform a wide variety of standard repetitive procedures without detailed technical supervision, usually in a well-established occupational field (i.e., chemistry, microbiology, etc.). They may also modify, vary or adapt standard procedures to meet the needs of research projects, or improve tests that are unsatisfactory, and after studying available literature, analyze and alter conditions under which determinations are made. They may also acquire and apply a body of knowledge and skill in a field of comparatively narrow scope where the emphasis is on specialized techniques.

To see the salary range for this position (we recommend that you make a note of the job code and use that to look up):TCS Non-Academic Titles Search (ucop.edu)

Please note: The compensation ranges listed online for roles not covered by a bargaining unit agreement are very wide, however a job offer will typically fall in the range of 80% - 120% of the established mid-point. An offer will take into consideration the experience of the final candidate AND the current salary level of individuals working at UCSF in a similar role.

For roles covered by a bargaining unit agreement, there will be specific rules about where a new hire would be placed on the range.

To learn more about the benefits of working at UCSF, including total compensation, please visit: https://ucnet.universityofcalifornia.edu/compensation-and-benefits/index.html

Department Description

The primary mission of the Cardiovascular Research Institute, the largest organized research unit on the San Francisco campus, is to promote fundamental and clinical research on the cardiovascular and pulmonary respiratory systems and to provide opportunities for postdoctoral training in these fields. With over 200 faculty, staff, and postdoctoral fellows, the CVRI supports faculty from a variety of departments (Medicine, Biochemistry, Biophysics, Lab Medicine, Pediatrics, Anatomy, Anesthesia, Pharmaceutical Chemistry, Physiology, Cellular and Molecular Pharmacology). The total extramural funding is $34 million annually (direct and indirect costs), with $1M in indirect cost return, and $561K in State funds. Assets include $38 million in endowment income and gifts, $3M in clinical reserves, and $5.8M in opportunity funds.

Required Qualifications

SRA I:

• BA/BS in a related science and knowledge of, or experience with, the basic techniques or methods required by the position; and/or an equivalent combination of education and experience;
• Knowledge or experience in basic laboratory skills gained or learned while in school or prior related experience: molarity calculations, accurate solution formulation, pH determination, maintenance of accurate notebooks, basic microbiological skills
• Knowledge or experience in molecular biology gained or learned while in school or prior related experience including but not limited to: bacterial transformation, PCR, real-time PCR, cloning, sub-cloning, site-directed mutagenesis, preparation and manipulation of DNA, DNA quantitation, agarose gel electrophoresis
• Knowledge or experience in protein expression gained or learned while in school or prior related experience including but not limited to: transformation, transfection, centrifugation, and SDS-PAGE, western blotting. Experience with column chromatography, detergents, and protein concentration, protein concentration determination,
• Knowledge or experience in multipanel flow cytometry
• Knowledge or experience in cell culture experience using eukaryotic cell lines
• Team player with good communication and interpersonal skills.  Willingness to learn and motivated to succeed

SRA II: In addition to above -

• BA/BS in a related science and one or more years of recent, directly related work experience, utilizing the techniques or methods required by the position; and/or equivalent experience/training.

Preferred Qualifications

• Staff Research Associate I: Prior experience as obtained while in school for the following: 
  • Animal handling skills, flow cytometry skills, and the desire to obtain primary data in addition to maintaining the lab
• Staff Research Associate II: In addition to meeting the required qualifications for an SRA II, prior experience of the above can be obtained while in school or outside of school.

About UCSF

The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world’s leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells.

Pride Values

UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence – also known as our PRIDE values.

In addition to our PRIDE values, UCSF is committed to equity – both in how we deliver care as well as our workforce. We are committed to building a broadly diverse community, nurturing a culture that is welcoming and supportive, and engaging diverse ideas for the provision of culturally competent education, discovery, and patient care. Additional information about UCSF is available at diversity.ucsf.edu

Join us to find a rewarding career contributing to improving healthcare worldwide.

Equal Employment Opportunity

The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.

Job Code and Payroll Title

009617 SRA 2 NEX

Job Category

Research and Scientific

Bargaining Unit

University Professional Technical Employees – Research Support Professionals Unit (UPTE-RX)

Additional Shift Details

Standard, M-F 40 hours per week, occasional weekend time may be required