Postdoctoral Fellow - Virology Research

City of Hope

Job Description

About City of Hope

City of Hope is an independent biomedical research and treatment organization for cancer, diabetes, and other life-threatening diseases.

Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope's translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution. AccessHope™, a subsidiary launched in 2019 serves employers and their health care partners by providing access to City of Hope's specialized cancer expertise.

A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation's "Best Hospitals" in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.

City of Hope's commitment to Diversity, Equity, and Inclusion

We believe diversity, equity and inclusion is key in serving our mission to provide compassionate patient care, drive innovative discovery, and advance vital education focused on eliminating cancer and diabetes in all our communities. Our commitment to Diversity, Equity and Inclusion ensures we bring the full range of skills, perspectives, cultural backgrounds, and experiences to our work -- and that our teams align with the people we serve to build trust and understanding. We are dedicated to fostering a community that embraces diversity - in ideas, backgrounds, and perspectives; this is reflected in our work and represented in our people.

Position Summary

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. Yuman Fong, at the Beckman Research Institute of City of Hope, a prestigious NCI-designated Comprehensive Cancer Center.

The candidate will directly work on oncolytic virus project, which involves assessing safety and anti-tumor efficacy of different viral constructs, in vitro and in mice. Oncolytic virotherapy is a major focus of our laboratory. The candidate will be working with our oncolytic poxvirus (CF33) and potentially other viral platforms.

Some of the tasks for this position include:

· Designing experimental plans

· Performing experiments to characterize oncolytic viruses. Experiments include amplification and purification of viruses, tissue culture, immune assays and tumor models in mice

· Studying oncolytic viruses in combination with immunotherapeutic agents

· Maintaining a good documentation of laboratory work

· Writing/amending regulatory protocols such as IACUC/IBC

Skills that are used in the lab include:

· Molecular engineering of viruses

· Immune assays

· Safety/efficacy testing of oncolytic viruses and immunotherapies in mice.

Basic education, experience and skills required for consideration:

· PhD in the field of Virology, Immunology, Oncology, Molecular biology, or other related areas, with a good understanding of cancer immunotherapy.

· Experience with basic virus-related work, molecular cloning, tissue culture, qPCR, Western blot etc.

· Experience with generation of recombinant viruses is desirable but not required.

· Experience with flowcytometry

· Experience with other immune assays such as ELISA and Elispot, is desirable

Additional Information:

As a condition of employment, City of Hope requires staff to comply with all state and federal vaccination mandates.

· To learn more about the research performed in Dr. Fong's lab please visit here:

The estimated pay scale represents the typical [salary/hourly] range City of Hope reasonably expects to pay for this position, with offers determined based on several factors which may include, but not be limited to, the candidate's experience, expertise, skills, education, job scope, training, internal equity, geography/market, etc. This pay scale is subject to change from time to time.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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