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Research Specialist - Kashuba Lab
Job Description
Posting Information
Posting Information
| Department | SOP-DPET-452200 |
|---|---|
| Career Area | Research Professionals |
| Is this an internal only recruitment? | No |
| Posting Open Date | 07/25/2023 |
| Application Deadline | 08/08/2023 |
| Position Type | Permanent Staff (SHRA) |
| Position Title | Research Specialist - Contributing |
| Salary Grade Equivalent | GN08 |
| Working Title | Research Specialist - Kashuba Lab |
| Position Number | 00052581 |
| Vacancy ID | P017875 |
| Full-time/Part-time Permanent/Time-Limited | Full-Time Permanent |
| If time-limited, estimated duration of appointment | |
| Hours per week | 40 |
| Work Schedule | M-F 8-5 |
| Work Location | Chapel Hill, NC |
| Position Location | North Carolina, US |
| Hiring Range | $43,337 - $52,967 |
| Pay Band Information | To learn more about the pay band for this branch and role, please see the Career Banding rates spreadsheet . |
Position Summary Information
| Primary Purpose of Organizational Unit | The UNC Eshelman School of Pharmacy at the University of North Carolina at Chapel Hill is the number one pharmacy school as ranked by U.S. News & World Report in its 2020 America’s Best Graduate Schools edition. We are a nationally recognized leader in progressive pharmaceutical care practice, education and research. The School enrolls approximately 600 Doctor of Pharmacy students, 80 Ph.D. students, and 20 master’s degree students. We maintain a robust research enterprise dedicated to finding new treatments for diseases and better ways of delivering health care. The School ranks second among the nation’s pharmacy schools in external research funding received. Our mission is to develop leaders in pharmacy education, pharmacy practice and the pharmaceutical sciences who make a difference on human health worldwide. The Division of Pharmacotherapy and Experimental Therapeutics in the UNC Eshelman School of Pharmacy is comprised of nationally recognized, dynamic and collegial faculty whose vision is to lead the nation in achieving excellence in innovative translational research, education, and progressive pharmacy practice to optimize drug therapy outcomes. Collaborative research opportunities exist with faculty in the Institute for Global Health and Infectious Diseases, Center for AIDS Research, Lineberger Comprehensive Cancer Center, Carolina Institute for Nanomedicine, Center for Pharmacogenomics and Individualized Therapy, and other programs in the Schools of Medicine, Public Health, Dentistry, Nursing and Pharmacy. These Schools comprise one of the nation’s few comprehensive academic health centers located on a world-class research campus. The Division has vibrant fellowship and graduate programs, including an NIH-funded T32 postdoctoral training program in Clinical Pharmacology in collaboration with Duke University and the UNC Institute for Drug Safety Sciences. The Kashuba laboratory supports the mission of the School and the Division by initiating and conducting research and scholarly activities in the area of HIV treatment, prevention and cure. The laboratory also develops clinical and translational scientists who generate, integrate and disseminate new knowledge to optimize drug therapy and improve health outcomes for the benefit of patients and society. This laboratory conducts preclinical and clinical research on HIV Treatment, Prevention and Cure, and is also Core Facility for the UNC Center for AIDS Research and the UNC Collaboratory of AIDS Researchers for Eradication (CARE). The Laboratory is CLIA (Clinical Laboratory Improvement Amendments) and CAP (College of American Pathologists)-approved, and maintains a team of bioanalytical chemists and scientists to develop and utilize cutting-edge LC-MS assays for small molecules. |
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| Position Summary | The University of North Carolina-Chapel Hill Eshelman School of Pharmacy is seeking a qualified analytical chemist for a full-time position as a research specialist within the Clinical Pharmacology and Analytical Chemistry Laboratory in the UNC Eshelman School of Pharmacy. The primary purpose of this position is to analyze biological samples for drug and endogenous compound concentrations, primarily by LC-MS/MS. These analyses support the grants and contracts of the Kashuba lab, the UNC Center for AIDS Research, and the UNC CARE Collaboratory for Eradication of HIV. Responsibilities of this position include: Analysis of biological samples by LC/MS/MS: * Perform timely, accurate and precise sample analysis using developed and validated bioanalytical methods (LC-MS/MS) of drug or endogenous compound concentrations in animal and human biological matrices. This includes conducting all aspects of the experiments, make deductions from resulting data and prepare detailed findings on results for quality assurance review and approval. * Maintain up-to-date laboratory records and documentation * Independently generate bioanalytical data from samples by accurately and independently following developed SOPs. * Preparation of stock solutions, calibrations standards, and QC samples for bioanalytical assays. * Extraction of study samples from biological matrices and quantitative analysis by LC-MS/MS. * Participation in method qualification and validation activities for new assays. * Participation in annual proficiency testing programs to maintain CAP and CLIA certification. Ensure rigorous and timely sample chain of custody and laboratory documentation: * Receive, verify, log-in and return/dispose (according to investigator preference) samples * Accurately and independently communicate service request data to the Laboratory team through updating weekly laboratory meeting agendas and real-time updating through Pipefy program management software * Archive study packets (by scanning, binding, and filing) in a timely and organized manner for easy retrieval. * Review, revise and draft pertinent SOPs * Ensure sample receipt is compliant with federal regulation by independently securing appropriate import permits (e.g CDC, USDA, etc.) |
| Minimum Education and Experience Requirements | Bachelor’s degree in a discipline related to the area of assignment; or equivalent combination of training and experience. All degrees must be received from appropriately accredited institutions. |
| Required Qualifications, Competencies, and Experience | The employee will be required to visually monitor their work in the laboratory for periods up to 4-5 hours at a time during sample extraction and data work-up and entry. Excellent manual dexterity is required. Experimental protocols must be followed with a high degree of accuracy in the conduct of all research activities. All experimentally obtained data must be accurately transcribed into notebooks and entered into sample manifests with 100% accuracy. High Level Communication Skills Written and verbal communication must be performed at a high level in the laboratory on a daily basis. The employee will have daily contact and a working relationship with other members of the laboratory: staff, graduate students, post-doctoral fellows, and research and clinical faculty. The employee will also have contact with research colleagues and collaborators and commercial vendors. |
| Preferred Qualifications, Competencies, and Experience | -Bachelor of science degree in a biological science such as biology, biochemistry, or analytical chemistry -Working experience in a GLP environment and experience in a BSL2 setting preferred. -Experience with LC-MS/MS, especially Sciex mass spectrometers, is preferred. -Proficiency with MS Office products (Word, Excel, PowerPoint). -Visual attention, mental concentration and manipulation skills -Excellent Safety Record |
| Required Licenses/Certifications | |
| Special Physical/Mental Requirements | Work will be conducting in a BSL2 environment. |
| Campus Security Authority Responsibilities | Not Applicable. |
| Position/Schedule Requirements | Exposure to Bloodborne Pathogens, Exposure to Hazardous Materials, Laboratory |
| Special Instructions | |
| Quick Link | https://unc.peopleadmin.com/postings/262329 |
Contact Information
| Office of Human Resources Contact Information | If you experience any problems accessing the system or have questions about the application process, please contact the Office of Human Resources at (919) 843-2300 or send an email to employment@unc.edu Please note: The Office of Human Resources will not be able to provide specific updates regarding position or application status. |
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| Equal Opportunity Employer Statement | The University of North Carolina at Chapel Hill is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender, gender expression, gender identity, genetic information, race, national origin, religion, sex, sexual orientation, or status as a protected veteran. |
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