The Translational Nanobiology Section of the Center for Cancer Research (CCR) at the National Cancer Institute (NCI) is leading efforts to comprehensively analyze extracellular vesicle subsets to determine which extracellular molecular components and signatures modulate anti-tumor immune responses and which may be targeted to improve cancer patient outcomes. In particular, the Section seeks to identify molecular signatures in advanced extracranial malignancies (systemic or metastatic cancers) that reflect the biological state of a patient’s cancer and physiological systems.

The Translational Nanobiology Section leverages several technologies developed in the Section and works collaboratively with a global multidisciplinary network of collaborators to systematically evaluate EV subset surface proteins and EV cargo RNA sequences. The NCI intramural program provides a unique environment for these studies because of how the NCI intramural program spans the range of translational research from high-risk basic research in immunology, tumor biology, and cancer data science, to paradigm-shifting clinical trials.

We are seeking a postdoctoral fellow to lead preclinical studies investigating extracellular vesicles as determinants of metastatic tumor spread and modulation of anti-tumor immune responses. Successful fellows will enthusiastically learn and develop new areas of expertise and will be highly collaborative, creative, conscientious, and self-motivated. Advanced skills with preclinical tumor models and data analysis are required in this fellowship. The position requires an M.D., D.V.M, Ph.D., or combination thereof in immunology, molecular/cell biology, liquid biopsies, experimental pathology, or related biomedical research. Prior training and publications in tumor biology, immunology, systems biology, and/or experimental pathology will be beneficial to candidates. We are looking for a candidate interested in conducting research at the interface of a wide range of disciplines to build new foundations for extracellular vesicle research.

This full-time training position is available immediately, with an appointment duration of up to 5 years. Please send a cover letter describing your research experience and interests, CV (with bibliography and start/end dates for all positions), and contact information for three references to: Dr. Jennifer Jones, email: jennifer.jones2@nih.gov .

The NIH is dedicated to building a community in its training and employment programs and encourages the application and nomination of qualified women, minorities, and individuals with disabilities.