The Position:

We are seeking a highly motivated Postdoctoral Fellow to join the Tao lab and the Membrane Protein group within the Department of Structural Biology at Genentech. The successful candidate will apply biochemical, biophysical and structural biology methods to investigate the structure-function of membrane proteins and membrane protein complexes relevant to human health and diseases. The Postdoc will work in a highly collaborative group, closely interfacing with research biology and technology labs to perform cutting-edge membrane protein research while being exposed to drug discovery in a world-class environment. The successful candidate will have access to X-ray crystallography, a state-of-the-art cryo-EM facility, exceptional resources and the opportunity to work in a highly stimulating and scientifically rich environment. Projects will involve groups across different therapeutic areas, both within Genentech and academia. The Postdoctoral Fellow’s seminal discoveries are expected to be published in top-tier journals and presented at external conferences.

Who You Are:

• PhD in structural biology, biochemistry, or a related field with one or more first-author publications in leading peer-reviewed journals.

• A strong background in protein biochemistry, with extensive hands-on experience and demonstrated success optimizing the expression and purification of proteins is required.

• Extensive experience with biochemical/biophysical characterization and structure determination of proteins by single-particle cryo-EM and/or X-ray crystallography is required.

• Experience of working with membrane proteins, using different extraction/reconstitution approaches and purification from native/endogenous sources, is desired.

• Experience with or strong interest in learning cryo-ET is a plus.

• Strong oral and written communication skills are essential.

• Self-motivated, independent, curious and rigorous researcher, willing to collaborate and learn new skills.

For more information about the Postdoctoral Program at Genentech, see:
https://www.gene.com/careers/university-and-early-career/postdocs

Recent relevant publications: Xiao Tao et.al PNAS 2023

This position is eligible for relocation benefits

The expected salary range for this position based on the primary location of California is $64,000 and $120,300.  Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.

Genentech requires all new hires to be fully vaccinated against COVID-19 as of their start date. This requirement is a condition of employment at Genentech, and it applies regardless of whether the position is located at a Genentech campus or is fully remote.  If you are unable to receive the vaccine due to a disability or serious medical condition, or because it is prohibited as a result of your sincerely held religious beliefs, you will have an opportunity to request a reasonable accommodation.