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Postdoctoral Scientist - Sutterwala and Cassel Lab - Lung Institute

Job Description


Are you looking to contribute to groundbreaking research? We invite you to consider this exciting opportunity to advance your career!

Principal Investigators, Fayyaz Sutterwala, MD, PhDand Suzanne Cassel, MD are looking for a Research Associate II to join a diverse team!

The focus of studies in the Sutterwala and Cassel Lab is a family of cytosolic molecules called nucleotide-binding domain leucine-rich repeat containing receptors (NLRs) that are involved in the regulation of innate immune responses and cell death pathways. To learn more, please visit the Sutterwala and Cassel Research Lab | Cedars-Sinai .

This position will study the role of immune pattern recognition receptors in cancer, other sterile inflammation, and host-pathogen interactions in human and mouse models. Research is focused on the molecular mechanisms employed by NLRs to regulate highly developed and adaptive immune responses, cell death, and senescence.

Some examples of research areas include:

  • Evaluating the contribution of mitochondria in innate immune signaling (Iyer et al. Immunity 2013; Elliott et al. J Immunol 2018).
  • Defining the role of macrophage and dendritic cell NLRC4 in controlling CD4 and CD8 T cell responses (Janowski et al. J Clin Invest 2016; Hornick et al. J Clin Invest 2019).
  • Evaluation of NLR function in cellular senescence in the setting of tissue repair.
  • Determining the roles of NLRs in the recruitment of neutrophils to inflammatory sites (Ulland et al. Nat Commun 2016).
  • The incumbent will perform routine and complex laboratory procedures throughout the training period. The Postdoctoral Scientist may develop, adapt, and implement new research techniques and protocols. This position is not responsible for generating grant funds, but fellowship application is encouraged.

    Primary Duties and Responsibilities:

    • Analyzes interpret, summarizes, and compiles data.
    • May assist in preparation of grant proposals, but is not responsible for generating grant funds.
    • May participate in publications and presentations as author or co-author.
    • Designs and performs experiments.
    • Maintains appropriate experimental records and documentation, and analyze the results with the Principal Investigator.
    • Analyzes, interprets, summarizes, and compiles data.
    • Operates and maintains equipment and instruments.

    Education:

    • Doctorate degree (MD, PhD, VMD, or DDS) in area directly related to field of research specialization.

    Experience:

    • Talents with a recent PhD or MD/PhD in biomedical sciences and experience in immunology, molecular biology, biochemistry, and/or murine models are encouraged to apply.
    • Experience with host-pathogen interactions, lipid biology, and/or wound repair are a plus.

    Physical Demands:

    Lifting, standing, walking


    Working Title:

    Postdoctoral Scientist - Sutterwala and Cassel Lab - Lung Institute


    Department:

    Home Dept - Pulmonary


    Business Entity:

    Cedars-Sinai Medical Center


    Job Category:

    Academic/Research


    Job Specialty:

    Postdoctoral


    Position Type:

    Full-time


    Shift Length:

    8 hour shift


    Shift Type:

    Day


    Base Pay:

    $64,500.00 - $93,600.00


    Cedars-Sinai is an Equal Employment Opportunity employer.

    Cedars-Sinai does not unlawfully discriminate on the basis of the race, religion, color, national origin, citizenship, ancestry, physical or mental disability, legally protected medical condition (cancer-related or genetic characteristics or any genetic information), marital status, sex, gender, sexual orientation, gender identity, gender expression, pregnancy, age (40 or older), military and/or veteran status or any other basis protected by federal or state law. If you need a reasonable accommodation for any part of the employment process, please contact us by email at Applicant_Accommodation@cshs.org and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.

    Cedars-Sinai will consider for employment qualified applicants with criminal histories, in accordance with the Los Angeles Fair Chance Initiative for Hiring.

    At Cedars-Sinai, we are dedicated to the safety, health and wellbeing of our patients and employees. This includes protecting our patients from communicable diseases, such as influenza (flu) and COVID-19. For this reason, we require that all new employees receive a flu vaccine based on the seasonal availability of flu vaccine (typically during September through April each year) as a condition of employment, and annually thereafter as a condition of continued employment, subject to medical exemption or religious accommodation. For the same reason, you may also be required to receive other vaccines such as COVID-19 as a condition of employment. Cedars-Sinai reserves the right to make modifications to its required list of vaccines as required by law and/or policy. Cedars - Sinai's EEO and AA Policy Statement


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