Researchers will be part of a highly collaborative team of motivated scientists and will be provided with supportive onboarding by experienced professionals. The researcher will be expected to collaborate and mutually support the other lab members to foster a fun and productive lab environment. The research professional is encouraged to think outside the box and challenge the PI in order to improve the overall scientific standards within the lab. The researcher is expected to spend 60% of their time doing wet lab experiments and 40% doing image analysis (analysis can be done at a PI-provided workstation or remotely).

Outstanding UA benefits include health, dental, and vision insurance plans; life insurance and disability programs; paid vacation, sick leave, and holidays; UA/ASU/NAU tuition reduction for the employee and qualified family members; state and optional retirement plans; access to UA recreation and cultural activities; and more!

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Duties:

• Design, organize, manage, and carry out analytical techniques and subsequent analysis to drive the PI's research. Design research methods in collaboration with senior researchers in Cellular and Molecular Medicine (CMM). Work with researchers to identify and recommend solutions to problems. 
• Use analyzed data to prepare research reports and support development of grant applications. 
• Perform protein expression using gel electrophoresis, western blot, enzyme linked immune sorbent assay (ELISA) recombinant protein expression. Study DNA/RNA expression, structure and function using PCR in various forms to study mutations, gene transcription and splicing. Study of organs, tissues and substructures at the macroscopic to ultrastructural level using primary human or murine tissue, with or without pathological assessment, histochemistry and immune-histochemistry.
• Carry out specialized techniques including super-resolution microscopy, electron microscopy, and immune hybridization. Study organoid properties from the whole mount level to the single cell level utilizing techniques such as whole muscle testing and permeabilized fiber testing.
• Assist and train PhD students and postdoctoral fellows to perform and design experiments and on the various techniques utilized in the lab. Direct and assist staff research technicians.
• Perform bench research including western blotting, RTPCR, extensive cell culture (including generation of primary cultures from patient samples), cell biological assays, and microscopy.
• Prepare buffers and reagents.
• Design and carry out single-cell imaging assays.
• Improve upon current image analysis techniques.
• Generate live-cell image analysis and collaborate with the UA Nikon center for excellence image analysis group.
• Manage supply inventory and order supplies when necessary.
• May manage other laboratory staff. 

Knowledge, Skills, & Abilities: 

• Willingness to learn new imaging and image analysis modalities.
• Ability to keep protocols, data, and samples organized with clear documentation recording how experiments were performed to ensure rigor and reproducibility.
• Ability to effectively communicate with professionalism with immediate peers within assigned work group and facilitate interaction and information exchange with other work groups as required to perform role. Based on nature of the role, employee may field requests from others in the organization.

• One (1) year of relevant work experience required.
• Bachelor's degree or equivalent advanced learning attained through experience required.