Details

Posted: 28-May-23

Location: Berkeley, California

Type: Full-time

Salary: Open

Categories:

Academic/Faculty
Business/Finance

Internal Number: 4225303

Assistant Project Scientist Drug delivery Department of Bioengineering
Position overview
Salary range: The UC academic salary scales set the minimum pay determined by step at appointment. See the following table(s) for the current salary scale(s) for this position: https://www.ucop.edu/academic-personnel-programs/_files/2022-23/july-2022-salary-scales/t38-b.pdf . A reasonable estimate for this position is $86,600-$100,300 annually.
Percent time: 100%
Anticipated start: Fall 2023
Position duration: 12 months. The appointment may be renewable depending on availability of funding and satisfactory performance.
Application Window
Open date: May 26, 2023
Next review date: Friday, Jun 9, 2023 at 11:59pm (Pacific Time)
Apply by this date to ensure full consideration by the committee.
Final date: Monday, Jun 26, 2023 at 11:59pm (Pacific Time)
Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.
Position description
The Department of Bioengineering at the University of California, Berkeley under the supervision of Professor Niren Murthy is seeking an Assistant Project Scientist to design and to assist in the development of different drug delivery systems in cell culture and animal models.
The successful candidate will assist driving the discovery of novel lipid nanoparticle (LNP) based delivery technology for RNA and DNA-based therapeutics to implement strategies to address the nucleic acid delivery challenges in vivo. LNPs formulations will be tested by delivering mRNA (EGFP, luciferase, Cas9, Cre, gRNA, base editors, prime editors, etc.) and plasmids in vitro and in vivo studies. The candidate will also develop engineered RNP/LNPs formulations for editing brain tissue to target various brain diseases/disorders. These formulations will be further improved/optimized by PEGylation and peptide linkage. The candidate will also provide training to undergraduate/graduate/and postdoc candidates and assist the principal investigator in grant writing, preparing manuscripts, and presenting results at various conferences.
Labor contract: https://ucnet.universityofcalifornia.edu/labor/bargaining-units/ra/contract.html
Qualifications
Basic qualifications (required at time of application)
Ph.D. or equivalent international degree
Preferred qualifications

• Ph.D. degree or equivalent international degree in Bioengineering
• Track record of peer reviewed publications in same or similar to this area.
• Experience in lipid nanoparticle/liposome synthesis and characterization.
• Experience in conducting in vitro cell-based assays and in vivo mouse studies.
• Experience in mouse organ harvesting, imagining, and quantification.
  
• Experience in synthesis of RNP and PEGylation studies.
• Extensive knowledge in bioconjugation (LNPs, Ab, Cas9, RNP, etc.) technologies by using commercial and in-house synthesized linkers.
• Experience in techniques such as size exclusion chromatography, UV/Vis, fluorescence, DLS, SDS-PAGE, PCR, nanoparticle characterization, etc.
• Good understanding of various genome editors (base and prime editors), guide RNA, plasmid designing tools, and various modifications. Also hands on experience in in vitro transcription is mandatory.
• Minimum two years postdoctoral experience

Application Requirements
Document requirements

• Curriculum Vitae - Your most recently updated C.V.
  
• Statement of Research
  

Reference requirements

• 3 required (contact information only)

Apply link: https://aprecruit.berkeley.edu/JPF03933
Help contact: jspitzer@berkeley.edu
Campus Information
Diversity, equity, inclusion, and belonging are core values at UC Berkeley. Our excellence can only be fully realized by faculty, students, and academic and non-academic staff who share our commitment to these values. Successful candidates for our academic positions will demonstrate evidence of a commitment to advancing equity, inclusion, and belonging.
The University of California, Berkeley is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy see: http://policy.ucop.edu/doc/4000376/NondiscrimAffirmAct
In searches when letters of reference are required all letters will be treated as confidential per University of California policy and California state law. Please refer potential referees, including when letters are provided via a third party (i.e., dossier service or career center), to the UC Berkeley statement of confidentiality prior to submitting their letter.
As a condition of employment, you will be required to comply with the University of California Policy on Vaccination Programs - With Updated Interim Amendments . All Covered Individuals under the policy must provide proof of receiving the COVID-19 Vaccine Primary Series or, if applicable, submit a request for Exception (based on Medical Exemption, Disability, Religious Objection, and/or Deferral based on pregnancy or recent COVID-19 diagnosis and/or treatment) no later than the applicable deadline. All Covered Individuals must also provide proof of receiving the most recent CDC-recommended COVID-19 booster or properly decline such booster no later than the applicable deadline. New University of California employees should refer to Exhibit 2 , Section II.C. of the SARS-CoV-2 (COVID-19) Vaccination Program Attachment for applicable deadlines. All Covered Individuals must also provide proof of being Up-To-Date on seasonal influenza vaccination or properly decline such vaccination no later than the applicable deadline. Please refer to the Seasonal Influenza Vaccination Program Attachment . (Capitalized terms in this paragraph are defined in the policy.) Federal, state, or local public health directives may impose additional requirements.
Positions that are represented by a collective bargaining unit or agent have particular contracts. For more information, please refer to the relevant contract: Lecturer (IX) contract , Postdoctoral (PX) contract , Academic Researcher (RA) contract , and Librarian (LX ) contract . Questions about represented positions can be directed to the hiring unit.
Job location
Berkeley, CA
To apply, visit https://aprecruit.berkeley.edu/JPF03933
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