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Postdoctoral Scientist- Burda Lab - Center for Neural Science and Medicine

Job Description


Principal Investigator, Joshua Burda, PhD, is looking for a Postdoctoral Scientist to join the team!

The Burda Lab explores how glia respond to injuries and disorders of the CNS and how these responses impact on neural repair, regeneration and neurological recovery. To learn more, please visit | BURDALAB.IO |.

The ideal candidate will investigate astrocyte-mediated molecular mechanisms underlying neural tissue remodeling, inflammation and regenerative plasticity of neural circuits after central nervous system (CNS) injury and in disease. This NIH-funded study has direct and important relevance to patients with traumatic brain injury, spinal cord injury, stroke or neurodegenerative diseases such as multiple sclerosis, in which therapeutically harnessing functions of injury-reactive astrocytes may be a key to improving outcome and promoting recovery.

Our research aimsto make use of multiple mouse models of nervous system injury and employ cell type-specific in vivo molecular manipulations, single cell RNA and ATAC sequencing, mouse transgenics, primary neuron, astrocyte and microglia culture, molecular biology, protein biochemistry, neuroanatomical tract tracing, histology, microscopy, and biobehavioral assessments in mouse models of CNS injury and degeneration.

Are you ready to be a part of breakthrough research?

Working independently but in close cooperation and in consultation with Dr. Burda and other Research Scientists, the Postdoctoral Scientist will perform routine and complex laboratory procedures throughout training period. Analyzes and interprets data. This is an outstanding opportunity to work with a multidisciplinary group of neuroscientists, neurologists, geneticists and bioinformaticians interested in identifying new therapeutic strategies for stimulating endogenous pathways of CNS repair and recovery. Postdoctoral Scientists in the Burda Lab also benefit from the groupsí well-established and ongoing collaborations with neighboring UCLA David Geffen School of Medicine and Brain Research Institute Investigators.

Primary Duties and Responsibilities:

  • May assist in the preparation of grant proposals, but is not responsible for generating grant funds.
  • May participate in publications and presentations as author or co-author.
  • Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator.
  • May develop, adapt, and implement new research techniques and protocols.
  • Analyzes interpret, summarizes, and compiles data.
  • Performs routine and complex laboratory procedures throughout the training period.
  • Operates and maintains equipment and instruments.
  • May observe MD-patient or MD-human research subject interactions as it pertains directly to research being performed.

Education:

  • Doctorate (MD, PhD, VMD or DDS) in an area related to the field of research specialization is required.

Experience and Skills:

  • Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment.
  • Works independently on research projects designed by a mentor (typically the PI) within area of specialization.
  • Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis and operation and maintenance of specialized equipment.
  • Knowledge of safety standards and maintenance of specialized equipment.
  • Experience with wet lab techniques including molecular biology, nucleic acid and/or protein biochemistry, cell and/or tissue culture.
  • Viral vector design and implementation (e.g. lentivirus, AAV or other).
  • R programming language and application for computational analysis of -omics datasets.
  • Disease modeling in rodents. Experience with rodent surgery is preferred, but not required.
  • Tissue processing and histological preparations for cellular and molecular analysis.

Working Title:

Postdoctoral Scientist- Burda Lab - Center for Neural Science and Medicine


Department:

BioMedical Science


Business Entity:

Cedars-Sinai Medical Center


Job Category:

Academic/Research


Job Specialty:

Postdoctoral


Position Type:

Full-time


Shift Length:

8 hour shift


Shift Type:

Day


Base Pay:

$64,500.00 - $93,600.00


Cedars-Sinai is an Equal Employment Opportunity employer.

Cedars-Sinai does not unlawfully discriminate on the basis of the race, religion, color, national origin, citizenship, ancestry, physical or mental disability, legally protected medical condition (cancer-related or genetic characteristics or any genetic information), marital status, sex, gender, sexual orientation, gender identity, gender expression, pregnancy, age (40 or older), military and/or veteran status or any other basis protected by federal or state law. If you need a reasonable accommodation for any part of the employment process, please contact us by email at Applicant_Accommodation@cshs.org and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.

Cedars-Sinai will consider for employment qualified applicants with criminal histories, in accordance with the Los Angeles Fair Chance Initiative for Hiring.

At Cedars-Sinai, we are dedicated to the safety, health and wellbeing of our patients and employees. This includes protecting our patients from communicable diseases, such as influenza (flu) and COVID-19. For this reason, we require that all new employees receive a flu vaccine based on the seasonal availability of flu vaccine (typically during September through April each year) as a condition of employment, and annually thereafter as a condition of continued employment, subject to medical exemption or religious accommodation. For the same reason, you may also be required to receive other vaccines such as COVID-19 as a condition of employment. Cedars-Sinai reserves the right to make modifications to its required list of vaccines as required by law and/or policy. Cedars - Sinai's EEO and AA Policy Statement


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