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Senior Research Investigator (Center for Cellular Immunotherapy)

Job Description


University Overview

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning. As an employer Penn has been ranked nationally on many occasions with the most recent award from Forbes who named Penn one of America’s Best Large Employers in 2023.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

Posted Job Title

Senior Research Investigator (Center for Cellular Immunotherapy)

Job Profile Title

Research Investigator, Senior

Job Description Summary

The Product Development Laboratory within the Center for Cellular Immunotherapies (CCI), seeks to hire a Senior Research Investigator to oversee the successful translation of cell and gene therapies from research bench to the clinic. This position reports to the Director of the Product Development Laboratory and is responsible for assisting in the strategic planning and the daily management of complex projects conducted with internal and external stakeholders. Responsibilities include laboratory operations such as training and supervision of research specialists, postdoctoral fellows, and student trainees to perform translational research, develop and execute study plans, perform data analysis, and conduct other aspects of quantitative and qualitative research.

Job Description

The Senior Research Investigator will be responsible for reviewing, editing, formatting, and writing manuscripts for publication, grant proposals, as well as compiling data packages and regulatory dossiers in support of Investigational New Applications.  The Senior Research Investigator will develop scope of works, create budgets, and execute project proposals while conducting research safely and in accordance with University policies and be responsible for timely completion of deliverables within established deadlines.    The Senior Research Investigator may also collaborate with other Principal Investigators within UPenn, CCI functional units (ie. Clinical Cell and Vaccine Production Facility, Human Genome Editing Laboratory, Science Operations, Translational Science and Correlatives Testing Laboratory). The ideal candidate will demonstrate strong analytical capabilities with solid written and verbal communication skills.   Finally, the ideal candidate should possess a comprehensive understanding of the current state of cell-based immunotherapies, clinical cell manufacturing and testing platforms, and genetic engineering and gene-editing technologies, in order to actively integrate emerging and novel concepts to drive innovation and advance the field.   

Qualifications:

Doctor of Medicine, Doctor of Philosophy, and 5 to 7 years of experience or equivalent combination of education and experience is required.

  • 5-7 years of relevant experience performing translational research
  • Strong background and publication record in the areas of human T cell immunology and cancer biology
  • Highly functioning, detail-oriented, and analytical candidate who can think strategically and holistically about technology and product development, and collaborative efforts across laboratories with CCI
  • Demonstrated experience developing and executing hypothesis-driven proposals, experiments with sound methodology and comprehensive controls, robust analyses and meaningful interpretations
  • Demonstrated experience and expertise in flow cytometry principles and applications, including multicolor panel design, cell sorting, data analysis softwares (ie. BD LSRFortessa, BD LSRII, BD FACSAria, BD FACSDiva, PRISM, FlowJo, and Microsoft Excel)
  • Demonstrated experience in mentoring, and training
  • Strong communication skills (verbal and written)
  • High-level of reliability and dependability
  • Self-starter with a strong desire to contribute and work collaboratively to achieve goals
  • Experience in handling and working with animal models required
  • Preferred understanding of product development as it relates to gene and cell therapy. Prior experience working in large, complex organizations such as the University of Pennsylvania. Prior experience with managing complicated research projects with multiple sub-teams of researchers

Job Location - City, State

Philadelphia, Pennsylvania

Department / School

Perelman School of Medicine

Pay Range

$36,368.00 - $94,753.00 Annual Rate

Salary offers are made based on the candidate’s qualifications, experience, skills, and education as they directly relate to the requirements of the position, as well as internal and market factors and grade profile. 

Affirmative Action Statement 
Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.

Special Requirements 
Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.

University Benefits

  • Health, Life, and Flexible Spending Accounts: Penn offers comprehensive medical, prescription, behavioral health, dental, vision, and life insurance benefits to protect you and your family’s health and welfare. You can also use flexible spending accounts to pay for eligible health care and dependent care expenses with pre-tax dollars.

  • Tuition: Take advantage of Penn's exceptional tuition benefits. You, your spouse, and your dependent children can get tuition assistance here at Penn. Your dependent children are also eligible for tuition assistance at other institutions.

  • Retirement: Penn offers generous retirement plans to help you save for your future. Penn’s Basic, Matching, and Supplemental retirement plans allow you to save for retirement on a pre-tax or Roth basis. Choose from a wide variety of investment options through TIAA and Vanguard.

  • Time Away from Work: Penn provides you with a substantial amount of time away from work during the course of the year. This allows you to relax, take vacations, attend to personal affairs, recover from illness or injury, spend time with family—whatever your personal needs may be.

  • Long-Term Care Insurance: In partnership with Genworth Financial, Penn offers faculty and staff (and your eligible family members) long-term care insurance to help you cover some of the costs of long-term care services received at home, in the community or in a nursing facility. If you apply when you’re newly hired, you won’t have to provide proof of good health or be subject to underwriting requirements. Eligible family members must always provide proof of good health and are subject to underwriting.

  • Wellness and Work-life Resources: Penn is committed to supporting our faculty and staff as they balance the competing demands of work and personal life. That’s why we offer a wide variety of programs and resources to help you care for your health, your family, and your work-life balance.

  • Professional and Personal Development: Penn provides an array of resources to help you advance yourself personally and professionally.

  • University Resources: As a member of the Penn community, you have access to a wide range of University resources as well as cultural and recreational activities. Take advantage of the University’s libraries and athletic facilities, or visit our arboretum and art galleries. There’s always something going on at Penn, whether it’s a new exhibit at the Penn Museum, the latest music or theater presentation at the Annenberg Center, or the Penn Relays at Franklin Field to name just a few examples. As a member of the Penn community, you’re right in the middle of the excitement—and you and your family can enjoy many of these activities for free.

  • Discounts and Special Services: From arts and entertainment to transportation and mortgages, you'll find great deals for University faculty and staff. Not only do Penn arts and cultural centers and museums offer free and discounted admission and memberships to faculty and staff. You can also enjoy substantial savings on other goods and services such as new cars from Ford and General Motors, cellular phone service plans, movie tickets, and admission to theme parks.

  • Flexible Work Hours: Flexible work options offer creative approaches for completing work while promoting balance between work and personal commitments. These approaches involve use of non-traditional work hours, locations, and/or job structures.

  • Penn Home Ownership Services: Penn offers a forgivable loan for eligible employees interested in buying a home or currently residing in West Philadelphia, which can be used for closing costs or home improvements.

  • Adoption Assistance: Penn will reimburse eligible employees on qualified expenses in connection with the legal adoption of an eligible child, such as travel or court fees, for up to two adoptions in your household.

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To learn more, please visit: https://www.hr.upenn.edu/PennHR/benefits-pay  


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