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Bioinformatics programmer 3

Job Description


Job Summary

We are recruiting a Bioinformatician Programmer 3 to participate on a multi-disciplinary research team with scientists and clinicians to develop tools to analyze large genomic data sets and other -omic data sets to facilitate the development of CRISPR gene therapy for neurologic disease. In this role, the bioinformatics programmer Uses skills as a seasoned, experienced bioinformatics programming professional with a broad understanding of computational algorithms and systems; identifies and resolves a wide range of issues / software bugs. Demonstrates good judgment in selecting methods and techniques for obtaining solutions. Operates independently in programming and data analysis and in close collaboration with the Clelland Lab.

The candidate will have expertise in data science and computer science. We will gather, analyze and interpret a wide variety of research data, including publicly available whole genome data sets, patient genome data sets, RNA data sets and proteomic data sets. Candidate will use data inference, data mining, analytics, data engineering and appropriate statistical methods. Proficiency with python, Java, SQL, Ruby, JavaScript (and TypeScript), C required. Familiarity with genomic data sets, VCF files, and genomic bioinformatics required. Candidate will build new bioinformatics tools to analyze genomic sequencing, RNA and protein data. Candidate will build an application from scratch that is cloud based and also web based (such as a website) and can be deployed locally on individual machines to protect PHI. Programmer will build an interface to analyze and visual genomic data sets for researchers. This includes population genomic data sets and individual patient genomic datasets. Application must be compatible with future data sets and apply across Cas enzymes/PAMs. This includes establishing and maintaining a server. All tools built and data analysis will be reported to PI, Claire Clelland.

We are recruiting a Bioinformatician Programmer 3 to participate on a multi-disciplinary research team with scientists and clinicians to develop tools to analyze large genomic data sets and other -omic data sets to facilitate the development of CRISPR gene therapy for neurologic disease. The candidate will have expertise in data science and computer science. We will gather, analyze and interpret a wide variety of research data, including publicly available whole genome data sets, patient genome data sets, RNA data sets and proteomic data sets. Candidate will use data inference, data mining, analytics, data engineering and appropriate statistical methods. Proficiency with python, Java, SQL, Ruby, JavaScript (and TypeScript), C required. Familiarity with genomic data sets, VCF files, and genomic bioinformatics required. Candidate will build new bioinformatics tools to analyze genomic sequencing, RNA and protein data. Candidate will build an application from scratch that is cloud based and also web based (such as a website) and can be deployed locally on individual machines to protect PHI. Programmer will build an interface to analyze and visual genomic data sets for researchers. This includes population genomic data sets and individual patient genomic datasets. Application must be compatible with future data sets and apply across Cas enzymes/PAMs. This includes establishing and maintaining a server. All tools built and data analysis will be under the supervision of the PI, Claire Clelland

To see the salary range for this position (we recommend that you make a note of the job code and use that to look up):TCS Non-Academic Titles Search (ucop.edu)

Please note: The compensation ranges listed online for roles not covered by a bargaining unit agreement are very wide, however a job offer will typically fall in the range of 80% - 120% of the established mid-point. An offer will take into consideration the experience of the final candidate AND the current salary level of individuals working at UCSF in a similar role.

For roles covered by a bargaining unit agreement, there will be specific rules about where a new hire would be placed on the range.

To learn more about the benefits of working at UCSF, including total compensation, please visit: https://ucnet.universityofcalifornia.edu/compensation-and-benefits/index.html


Department Description

Throughout the Department of Neurology at UCSF, our mission is to deliver superb patient care, to apply state-of-the-art translational research methods to discover the causes of and treatments for human nervous system disorders, and to educate each generation of medical students, neurology residents and postdoctoral fellows. By fostering cross-disciplinary interactions among scientists around the world, we accelerate the pace of discovery and champion the University's global health initiatives.


Required Qualifications

  • Bachelor's degree in biological science, computational / programming, or related area and minimum three years of experience / or equivalent experience / training obtained or expected to be obtained by the start date.
    • Experience with whole genome data sets AND:
    • Programming Languages: Python, Java, SQL, Ruby, JavaScript (and TypeScript), C
    • Databases: PostgreSQL, Redis and MongoDB (NoSQL)
    • Full Stack Web Development: Docker, Azure, Flask, Ruby on Rails, React, Ember.js, CSS, HTML
    • Data Science: Spark, PyTorch, Jupyter/DataSpell, NumPy, SciPy, pandas, xarray, scikit-learn, statsmodels, Matplotlib, Seaborn, CARTO (GIS), Excel
  • Communication skills to work with both technical and non-technical personnel in multiple fields of expertise and at various levels in the organization.
  • Ability to communicate technical information in a clear and concise manner.
  • Ability to interface with management on a regular basis.
  • Self motivated, work independently or as part of a team, able to learn quickly, meet deadlines and demonstrate problem solving skills.
  • Thorough knowledge of web, application and data security concepts and methods.
  • Thorough knowledge of bioinformatics methods, applications programming, web development and data structures.
  • Thorough knowledge of bioinformatics programming design, modification and implementation.
  • Understanding of relational databases, web interfaces, and operating systems.
  • Strong project management skills.

Preferred Qualifications

  • Thorough knowledge of modern biology and applicable field of research.

About UCSF

The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world’s leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells.


Pride Values

UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence – also known as our PRIDE values.

In addition to our PRIDE values, UCSF is committed to equity – both in how we deliver care as well as our workforce. We are committed to building a broadly diverse community, nurturing a culture that is welcoming and supportive, and engaging diverse ideas for the provision of culturally competent education, discovery, and patient care. Additional information about UCSF is available at diversity.ucsf.edu

Join us to find a rewarding career contributing to improving healthcare worldwide.


Equal Employment Opportunity

The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.


Job Code and Payroll Title

009401 BIOINFORMATICS PROGR 3


Job Category

Clinical Systems / IT Professionals, Research and Scientific


Bargaining Unit

99 - Policy-Covered (No Bargaining Unit)


Additional Shift Details

Monday – Friday, 8:00 AM – 5:00 PM


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