Applications are invited for a Postdoctoral Research Associate at the Upadhyaya lab (arpitalab.github.io ) at the University of Maryland, College Park.

The lab is broadly interested in mechanobiology, specifically how cells and tissues respond to the physical properties of their microenvironment. While our primary focus is on immune and cancer cells, we welcome creative ideas beyond what the lab currently works on and that complement our strengths. The successful candidate will have the freedom to design their project within the broad outlines of the lab's interest areas and will be responsible for the day-to-day running of the project.

A potential project would be to investigate chromatin and transcription factor dynamics using single-molecule imaging, biophysical, and molecular biology approaches. The project aims to uncover how factors in the cellular microenvironment regulate chromatin accessibility and transcription factor mobility, organization and binding in cancer and immune cells. We work in close collaboration with the Hager laboratory at the NIH.

Applicants should possess (or be close to obtaining) a PhD in Physics, Biophysics, Bioengineering or a related field. Familiarity with biochemical and biophysical approaches to study DNA-protein interactions and/or imaging to study cell and protein dynamics would be desirable. Experience with programming and image data analysis in MATLAB or Python is a plus.

Interested individuals should email a cover letter, a description of past research and future goals and their CV with a list of three references to Dr. Arpita Upadhyaya (arpitau@umd.edu ).

The Upadhyaya lab is an open and inclusive environment and is dedicated to the career development of scientists, whether they wish to remain in academia or not.