Department of Cardiology

Full Time

71937BR

Job Summary

The Staff Research Associate III (SRA III) assist the principal investigator (PI) with active experiments and the daily tasks related to the operation of a biomedical research laboratory with potential to eventually move into a lab manager role.

Our research effort is focused on understanding the gene-regulatory and epigenetic mechanisms that govern early cell fate decisions during cardiogenesis and cell state transitions in the setting of adult pathologic remodeling. To do this, we have generated and are generating several novel lines of mice and stem cells that harbor genetic alterations at specific loci which will allow us to investigate the roles for a family of histone acetyl-lysine reader proteins in these processes. Using both cutting-edge genome-scale techniques as well as traditional in vitro and in vivo assays, we will begin to dissect aspects of the chromatin regulatory mechanisms that govern early cardiac development and pathologic remodeling in heart failure.

The SRA III will have many duties relevant to these goals including generation of DNA constructs, manipulation of mouse embryos, mouse colony maintenance, and the use of standard developmental biology, cell culture, and molecular biology techniques to analyze tissues and cells.

To see the salary range for this position (we recommend that you make a note of the job code and use that to look up):TCS Non-Academic Titles Search (ucop.edu)

Please note: The compensation ranges listed online for roles not covered by a bargaining unit agreement are very wide, however a job offer will typically fall in the range of 80% - 120% of the established mid-point. An offer will take into consideration the experience of the final candidate AND the current salary level of individuals working at UCSF in a similar role.

For roles covered by a bargaining unit agreement, there will be specific rules about where a new hire would be placed on the range.

To learn more about the benefits of working at UCSF, including total compensation, please visit: https://ucnet.universityofcalifornia.edu/compensation-and-benefits/index.html

Department Description

The Department of Cardiology is the largest department in the UCSF School of Medicine. To advance health, the Department of Medicine develops and supports innovators in patient-centered care, scientific discovery, medical education and public policy across five main sites (Mission Bay, Parnassus, ZSFG, VAMC, and Mt. Zion) and 39 divisions. The Division of Cardiology is one of the largest clinical, research and training divisions of the Department of Medicine (DOM) at UCSF. Within the Division are sub-specialty sections for: Adult Congenital Heart Disease; Advanced Heart Failure, Transplant, and Pulmonary Hypertension; Cardiac Electrophysiology; Echocardiography and Cardiac Imaging; General Cardiology, Interventional Cardiology; and Prevention. The Division runs several clinical practices in multiple sites, conducts basic and clinical research via large clinical, Federal, and privately supported research programs and six faculty laboratories, and educates medical students, residents, clinical fellows and postdoctoral scholars through ACGME as well as non-ACGME training programs.

Required Qualifications

• BA/BS degree with a major in a related science field (background in general biology, molecular biology, cell biology, genetics, and chemistry) and two or more years of recent, directly related work experience following degree completion, utilizing the techniques or methods required by the position and demonstrating technical expertise in these areas; or an equivalent combination of education and experience
• Experience with mouse colony maintenance
• Experience with basic molecular cloning and biochemistry
• Experience with basic cell culture techniques
• Experience accurately and successfully performing the collection, processing, and sectioning of histologic specimens; antibody staining of histologic specimens; imaging and analysis of stained tissues; DNA and protein gel electrophoresis; Western blotting; PCR; standard cell culture; and DNA/RNA extractions from animal tissues and cell culture samples
• Demonstrated knowledge of molarity, sterile technique, standard Mendelian genetic inheritance, and general microbiology
• Demonstrated ability to perform standard data analysis
• Demonstrated ability to multi-task

Preferred Qualifications

• Master’s degree in a field relevant to biomedical research
• Experience with rodent surgery
• Previous lab manager experience

About UCSF

The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world’s leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells.

Pride Values

UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence – also known as our PRIDE values.

In addition to our PRIDE values, UCSF is committed to equity – both in how we deliver care as well as our workforce. We are committed to building a broadly diverse community, nurturing a culture that is welcoming and supportive, and engaging diverse ideas for the provision of culturally competent education, discovery, and patient care. Additional information about UCSF is available at diversity.ucsf.edu

Join us to find a rewarding career contributing to improving healthcare worldwide.

Equal Employment Opportunity

The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.

Job Code and Payroll Title

009611 SRA 3

Job Category

Research and Scientific

Bargaining Unit

University Professional Technical Employees – Research Support Professionals Unit (UPTE-RX)

Additional Shift Details

Monday - Friday, 8:00am - 5pm and occasional weekends