This job has Expired
Postdoctoral Research Associate
GENERAL REQUISITION INFORMATION
|EEO Statement:|| |
UNMC is an Affirmative Action Equal Employment Opportunity Employer, including an equal opportunity employer of protected veterans and individuals with disabilities.
|Department||Pharmacology/Exp Neuroscience 50000523|
|Business Unit(College/Institute)||College of Medicine|
|Work Schedule||TBD by research needs|
|Requisition Category||Research - Academic|
|Requisition Title||Postdoctoral Research Associate|
|Job Title/Academic Rank||Postdoctoral Research Associate|
|Additional Requisition Title|
|Appointment Type||A1 - REG OTHER ACAD SAL|
|Salary Range||Salary Commensurate with Experience|
|Job/EEO Category||Professional Non-Faculty (Includes Other Academic)|
|Job Requisition Begin Date||03/17/2023|
|Position Summary|| |
Immediate opening for a highly motivated postdoctoral research associate to join a developing molecular biology group for delivery of CRISPR Therapeutics towards HIV elimination. The research seeks to merge revolutionary CRISPR-Cas9 technology with state-of-the-art nanoformulation technologies for targeted excision of integrated proviral DNA. Knowledge in recombinant DNA technologies, gene delivery, and mRNA CRISPR/Cas9 is required. Experience in HIV-1 biology and disease pathogenesis is helpful but not mandatory. To accelerate established efforts, team requires the candidate to partner with on-site scientists with virological, animal model and theranostic expertise. The program was the first the eliminate HIV-1 from a live animal and seeks to extend prior successes with improved gene recognition, delivery and exclusion of off-target toxicities. The overarching goal is HIV cure with a focus on CRISPR based gene editing of virus, viral receptors and required transcriptional factors.
|Required Qualifications|| |
Ph.D. in Molecular or cell biology, immunology or related field.
Knowledge in recombinant DNA technologies, gene delivery, and mRNA CRISPR/Cas9 is required.
Experiences in basic and applied molecular biology and prior mRNA or CRISPR-Cas9 research knowledge required for system characterization.
|Supplemental Qualifications|| |
Experience in HIV-1 biology and disease pathogenesis is helpful but not mandatory.
PCR, qPCR, western blot, cloning, cell culture.
Strong knowledge mRNA based gene editing.
Research experience with mice would be desirable
The candidate should have basic understanding of CRISPR Cas9 based gene editing (knock out knock in). Prior expertise in lentiviral/CRISPR vector design is preferred. Providing oversight and troubleshooting in basic and applied molecular biology is required that include, but not limited to, DNA/RNA extraction, restriction digestion, PCR, RT-qPCR, virus production, viral titration, transformation, transfection and transduction. The ability to work independently and cooperatively is essential. Candidates must have good writing and communication skills. Ample opportunities for career development, grant writing and faculty appointments possible.
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