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Postdoctoral Associate - UF/Genentech

University of Florida

Job Description


Classification Title:

Postdoctoral Associate - UF/Genentech

Job Description:

We are seeking self-motivated applicants for a two-year post-doctoral fellowship position in the area of clinical pharmacokinetics/pharmacodynamics. The position will be supported through a joint fellowship program between the Clinical Pharmacology Department at Genentech and the Center for Pharmacometrics & Systems Pharmacology at the University of Florida. A key objective of the Fellowship is to integrate the academic and industry experience in clinical pharmacology and modeling & simulation (M&S) research. To that end, the Fellowship has two goals - a training goal and a project goal. To achieve these goals, the Fellow will have mentors at both Genentech and at the University of Florida.

The successful candidate with have the opportunities to participate in:

  • Participate in weekly project meetings to gain experience in:

    • Effectively analyzing, interpreting, and presenting Pharmacokinetics (“PK”) and Pharmacodynamics (“PD”) data at cross-functional teams, Department meetings, and regulatory meetings. Data analysis activities could include non-compartmental analysis, statistical analysis, population PK/PD models, disease models, physiological-based PK (PBPK) models, quantitative system pharmacology (QSP) models, clinical trial simulations, literature meta-analysis, machine learning/deep learning, and other state-of-the-art quantitative techniques.
    • Developing a clinical pharmacology plan and/or modeling & simulation plan
    • Leading and contributing to the design and review of clinical pharmacology clinical study protocols and analysis plans
    • Preparing and reviewing Clinical Pharmacology or Modeling & Simulation sections of the study reports and other internal, clinical, and regulatory documents
    • Perform other duties as directed by University of Florida and Genentech
  • Participate in didactic instruction that supplements training and personal interest.  Course topics include but are not limited to biostatistics, advanced pharmacokinetics, drug metabolism, drug analysis, or epidemiology

  • Participate in regular group meetings at Genentech and/or the University of Florida
  • Expected Salary:

    Salary as defined by NIH guidelines, and based on education and experience.

    Minimum Requirements:

    Ph.D. in Pharmaceutical Sciences, Health Science, Engineering, Statistics, Applied Mathematics or related fields or Pharm.D. or M.D. with knowledge of PK/PD analyses. 

    Preferred Qualifications:
    • Hands-on experience with nonlinear mixed-effect modeling (NONMEM)
    • Experience with NONMEM, R, Phoenix, Monolix, Pumas, SimBiology, Simcyp, GastroPlus, Python, or other related software packages
    • Experience with conducting independent and/or collaborative research
    • Interest in interdisciplinary research
    • Strong communication skills
    Special Instructions to Applicants:

    In order to be considered, you must upload your CV/resume, cover letter, and list of at least 3 professional references.

    Please note, this position is housed at the UF Research and Academic Center in Orlando, FL.

    Application must be submitted by 11:55 p.m. (ET) of the posting end date.

    Health Assessment Required: No

     


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