A full-time position is available for a project manager in the laboratory of Dr. Brian Crompton in the Department of Pediatric Oncology at the Dana-Farber Cancer Institute. The Crompton laboratory uses a combination of next-generation sequencing and proteomic approaches to profile tumor material from matched tumor biopsies, circulating tumor DNA, and circulating tumor cells. These studies are focused on understanding the genomic, proteomic, and epigenomic heterogeneity and disease evolution of pediatric solid tumors and leveraging that understanding to develop new pharmacodynamic markers of drug activity and discover mechanisms of treatment resistance. The laboratory works with an extensive network of clinical investigators running multi-institutional clinical trials from which well-annotated patient samples are obtained. The laboratory is well supported by National Cancer Institute, Department of Defense, and Foundation grants. 

Consideration will be given to less experienced applicants which may influence the job level to be changed to an entry level Research Project Manager. Persons with knowledge of clinical research regulatory affairs are especially encouraged to apply.

We are seeking a highly motivated individual to coordinate our collaborative studies that are dependent on receiving, processing, and profiling patient samples collected from numerous multi-institutional trials. These trials originate both from Dana-Farber Cancer Institute as well as national clinical trial consortiums. This position will require adaptability to fast-paced research environment, ability to function in a highly collaborative environment, excellent communication, organizational, and computer skills, and a comfort with learning about new scientific technologies.We expect all the responsibilities associated with this position to be amenable to working remotely. Responsibilities will include:

• Drafting and amending requests for tissue samples from established biorepositories including the Children’s Oncology Group biopathology center and Boston Children’s Hospital biorepository
• Submitting research projects to the Dana-Farber Cancer Institute’s Internal Review Board (IRB) to receive approval for human subjects research or for determination of non-human subjects research
• Initiating and coordinating material and data transfer agreements between Dana-Farber’s legal office and our collaborators
• Coordinating and communicating tissue sample transfers coming into the laboratory and samples/data going from the lab to collaborators at other institutions.
• Facilitating communication between the laboratory research team and the clinical research team to coordinate tissue collection from enrolled patients
• Working with the finance team to execute payments to the various core laboratories where many of our profiling experiments are performed
• Assisting the PI and fellows with the preparation of grant applications and manuscripts
• Collaborate closely with team members to help develop, streamline, and implement data analysis plans
• Responsible for development and maintenance of study-related databases
• The project manager will be expected to develop a sophisticated understanding of the research being performed with the goal of facilitating and accelerating research progress

• Bachelor’s degree required in a field relevant to clinical research.
• 2 years (minimum) of experience in a related field including roles that involve consenting patients to research studies, conducting translational laboratory research, managing biobanking protocols, or other involvement in research that utilizes patient samples.
• Must have strong knowledge of regulatory affairs, research ethics and the responsible conduct of research.
• 5 plus years experience with project management and experience working on clinical trials (multi-center, oncology trials perferred).
• Experience in an academic institution and proven history of success in clinical research field is preferred.

At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong.  As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff.  Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.