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Postdoctoral Research Associate - Infectious Diseases

University of Washington

Job Description


Job Description

Position Summary

Two full-time postdoctoral fellow positions are available immediately at Dr. Chen Shen’s lab in the Division of Infectious Disease, Department of Medicine at Washington University in St. Louis.

Dr. Shen graduated from Peking University with a Ph.D. in physical chemistry and structural biology, completed his postdoctoral training at Harvard Medical School and Boston Children’s Hospital, and joined Washington University School of Medicine in January 2023. He has an excellent track record in biochemistry, structural biology, and inflammasome biology, demonstrated by the selected first/co-first author papers: Shen, Li et al ., Cell, 2021; Shen et al ., PNAS, 2019; Shen, Vohra et al. , PNAS, 2021; Zheng, Shen, Wang, Rawson et al., Science Advance, 2022.

Shen lab focuses on studying the molecular mechanisms of host-pathogen interaction using structural and biochemical tools with the ultimate goal to provide the foundation for the development of therapeutics targeting inflammatory bowel disease and various infectious diseases. The major questions include: 1. How do virulence factors produced by pathogens hijack the host protein (HIV infection, gram-positive bacterial infection)? 2. How do innate immune receptors (NOD-like receptors) sense pathogen-associated molecular patterns? We are also interested in studying the mechanisms of infection-induced chronic diseases in the long term.

Washington University in St. Louis is a prestigious research university founded in 1853. The Division of Infectious Disease is a national leader in infectious disease research, making tremendous contributions to the fight against SARS-CoV-2 through mechanistic studies and vaccine development. Shen lab will establish extensive collaborations with PIs in the department of medicine, molecular microbiology, biochemistry, pathology and immunology, genetics, and developmental biology. The exceptional academic environment and strong connections will nurture the growth of scholars.

Located in the heartland of the United States, St. Louis is one of the most affordable U.S. cities to live in, with vibrant music, impressive Midwestern food, and beautiful scenery. In recent years, St. Louis has become one of the top-rising cities for startups, according to Forbes, and in 2021, TIME named the city as the world’s greatest place. WashU’s medical campus borders Forest Park, one of the largest urban parks in the country. The park includes city’s art museum, zoo, science center, and other free attractions, offering an expansive area to explore recreational and cultural interests. Here, the excitement and amenities of a big city are readily available without the high cost of living.

We are seeking enthusiastic individuals to join the lab with a friendly and supportive atmosphere. The expected starting date will be the Spring/Summer of 2023.

Information on being a postdoc at Washington University in St. Louis can be found at https://postdoc.wustl.edu/prospective-postdocs-2/ .

Required Qualifications

  • Ph.D. in biological science or a related field.
  • Strong background in protein biochemistry, cell biology, or structural biology.
  • Proven track record of publications and excellent written and oral communication skills.

Preferred Qualifications

Experience in mammalian cell culture, and/or cryo-EM/EM data processing.

Working Conditions

This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals.

Salary Range

Base pay is commensurate with experience.

Applicant Special Instructions

To apply, please email the information below to Dr. Chen Shen at shenc@wustl.edu :

  • CV including the description of technical expertise.
  • Cover letter describing your past and current research activity, and a brief statement of achievements.
  • Contact information of three references.


Accommodation

If you are unable to use our online application system and would like an accommodation, please email CandidateQuestions@wustl.edu  or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.


Pre-Employment Screening
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.


Benefits Statement
Washington University in St. Louis is committed to providing a comprehensive and competitive benefits package to our employees. Benefits eligibility is subject to employment status, full-time equivalent (FTE) workload, and weekly standard hours. Please visit our website at https://hr.wustl.edu/benefits/ to view a summary of benefits.


EEO/AA Statement
Washington University in St. Louis is committed to the principles and practices of equal employment opportunity and especially encourages applications by those from underrepresented groups. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.


Diversity Statement
Washington University is dedicated to building a diverse community of individuals who are committed to contributing to an inclusive environment – fostering respect for all and welcoming individuals from diverse backgrounds, experiences and perspectives. Individuals with a commitment to these values are encouraged to apply.

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