The Obeng Laboratory is seeking creative and highly motivated candidates for a fully supported postdoctoral fellowship studying the pathogenesis of myeloid malignancies. The major interests of the lab are determining how acquired mutations in hematopoietic stem cells lead to the development of clonal hematopoiesis, myelodysplastic syndrome, and leukemia, in addition to identifying and studying novel treatments that selectively target malignant clones.

You will have the opportunity to develop and lead projects using several cutting-edge model systems including:

• Isogenic immortalized cell lines generated using CRISPR-Cas gene editing
• Novel xenograft and transgenic in vivo systems
• Induced pluripotent stem cells
• Primary patient samples

In this position, you will gain extensive experience and training in genomics, stem cell biology, computational biology and pre-clinical study development. The Obeng lab is a highly collaborative and interactive environment focused on the scientific development of trainees. Our lab supports and encourages diversity and promotes career development.

St. Jude Children’s Research Hospital is a top-ranked Pediatric Cancer Hospital and a world-renowned basic science research institute with over 200 faculty members. St. Jude offers a highly collaborative research and training environment that includes state-of-the-art facilities and resources. Postdoctoral research fellows are provided with a competitive salary, excellent benefits, and a professional development allowance. 

Minimum Education

Successful applicants will have a Ph.D. in molecular biology, cell biology, genetics or a related field; a strong publication record; and excellent communication skills. To succeed in this position, applicants must have a strong cell and molecular biology background and an interest in working with in vivo model systems. Applicants with expertise in genome editing, RNA biology, computational biology, and working with hematopoietic stem cells are encouraged to apply.

Other Information