A Postdoctoral Scholar position is available under joint supervision between two departments (Ophthalmology and Visual Sciences/Dr. Mark Greiner and Pharmaceutical Sciences and Experimental Therapeutics/Dr. Aliasger Salem). Research areas include i) drug discovery and drug development research for the treatment of corneal diseases, ii) developing genetically modified animal models of corneal disease, iii) identifying novel therapeutic targets and mechanisms for translational research. The laboratory employs genetic mouse models, cell culture systems, and multidisciplinary approaches ranging from Biomedical Engineering, Cell Biology, and Pharmaceutical Sciences. Applicants should have solid conceptual and research backgrounds in one or more of the following areas: cellular biology, pharmaceutical sciences, drug design, tissue engineering, biomedical engineering, chemical engineering, or in a related discipline. Individuals who are highly motivated and willing to take risks for innovation are encouraged to apply. Successful candidates are expected to work independently, yet in a collaborative environment with a group of scientists with various areas of expertise.

KEY AREAS OF RESPONSIBILITIES:

Research

Work independently on basic research tasks with oversight by Principal Investigator(s) (PI).

Investigate pathophysiological mechanisms using cell culture systems and mouse models.

Conduct biochemical and cell biological experiments.

Develop novel approaches to investigate protein-protein interactions and disease mechanisms.

Collect and analyze experimental data and evaluate relevance of the data.

Compare experimental data with published work and develop and test new hypotheses.

Contribute to documentation of equipment and procedures.

Collaborate with students and other members of the laboratory

Dissemination of Research Results

Prepare/assist in preparation of manuscripts for publication.

Present results in departmental seminars and at scientific meetings.

Research Proposals/Grants

Contribute to new or continuing research grant proposals to obtain funding for research activities.

May serve as co-PI on grants or proposals.

Contribute to progress reports required by funding agencies.

Supervise adherence to safety and compliance guidelines when necessary.

A PhD degree in Molecular and Cell Biology, Pharmaceutical Sciences, Biomedical Engineering, or a related field is required.

• 4-5 years of hands-on research experience in one or more of the following: molecular and cellular biology, pharmaceutical sciences, drug design, tissue engineering, biomedical engineering, chemical engineering, or in a related discipline.


• Proficient in standard molecular biology techniques (e.g. RT-PCR, DNA and RNA isolation, quantitative Real Time PCR, HPLC, cell culture, animal handling), common biochemical techniques (e.g. expression and purification of recombinant proteins, protein isolation and purification from human and mouse tissue samples), common cell biology techniques (e.g. immunofluorescence, western blotting/immunohistochemistry) and tissue culture techniques (i.e. establishing and maintaining primary cell lines and generating stable cell lines).


• Excellent oral, written, and interpersonal skills.


• Peer reviewed record of scientific productivity.

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