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Postdoctoral Fellow in Pharmacology & Toxicology (Parasitic Disease Research)
Job Description
Posting Details
Position Details
| Title | Postdoctoral Fellow in Pharmacology & Toxicology (Parasitic Disease Research) |
|---|---|
| Specific Title | |
| Appointment Type | Postdoctoral Fellow |
| Department | IUSM - Pharmacology & Toxicology |
| Campus | IU School of Medicine Indianapolis |
| Position Summary | “Cellular signaling and gene expression in the parasite Toxoplasma gondii" We are accepting applications for a postdoctoral fellow interested in the study of cellular signaling and the regulation of gene expression in the protozoan parasite Toxoplasma gondii. Toxoplasma is an opportunistic pathogen that causes severe disease in congenitally infected infants and immune compromised patients. Toxoplasma is a significant clinical challenge because the parasite converts into a latent tissue cyst form that evades immunity and current drugs. The tissue cysts are central to pathogenesis, transmission, and behavioral changes in the host. Our laboratory seeks to solve this clinical problem by obtaining a better understanding of the mechanisms driving tissue cyst formation. We use state-of-the-art multi-disciplinary approaches to interrogate how the parasite alters translation and reprograms its genome to convert to the latent stage of infection. The successful applicant will contribute to exciting projects examining the myriad ways gene expression is regulated in the context of cyst formation. This includes study of multiple mechanisms including transcription, epigenetics, epitranscriptomics, and translational control. Our long-term goal is to identify novel points of therapeutic intervention that will thwart the development and maintenance of Toxoplasma tissue cysts This is a NIH position in the laboratory of Bill Sullivan https://wjsulliv.wixsite.com/sullivanlab Our laboratory is a part of the “BIP” (Biology of Intracellular Pathogens) group at the Indiana University School of Medicine (IUSM): http://wjsulliv.wix.com/bipatiu . As the nation’s largest medical school, IUSM is committed to being an institution that not only reflects the diversity of the learners we teach and the patient populations we serve, but also pursues the values of diversity, equity and inclusion that inform academic excellence. We desire candidates who enhance our representational diversity, as well as those whose work contributes to equitable and inclusive learning and working environments for our students, staff, and faculty. IUSM strives to take an anti-racist stance, regularly evaluating and updating its policies, procedures, and practices to confer equitable opportunities for contribution and advancement for all members of our community. We invite individuals who will join us in our mission to advance racial equity to transform health and wellbeing for all throughout the state of Indiana. Indianapolis is the capital and most populous city in the State of Indiana. It is growing economically thanks to a strong corporate base anchored by the life sciences. Indiana is home to one of the largest concentrations of health sciences companies in the nation. Indianapolis has a sophisticated blend of charm and culture with a wonderful balance of business and leisure. The growing residential base is supported by rich amenities and quality of life – the city possesses a variety of professional sports, arts venues and outdoor recreation areas. Residents of this dynamic city, and surrounding suburbs, enjoy leading educational systems and top-ranked universities, paired with a diverse population. Indianapolis International Airport is a top-ranked international airport, being named “Best Airport in North America” by Airports Council International for many years. For additional information on life in Indy: https://faculty.medicine.iu.edu/relocation The search committee will begin evaluating applications as they are received and applications will continue to be reviewed until positions are filled. |
| Basic Qualifications | A doctorate degree is required. |
| Department Contact for Questions | Susan Voight, svoight@iupui.edu |
| Additional Qualifications | |
| Special Instructions | Please include a cover letter, recent CV, and names and contact information for three references. |
| Priority Application Review Deadline | |
| Expected Start Date | |
| OAA # | IUSM-01569-2022 |
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