Position Description:

Applications are sought for a postdoctoral fellow position in research groups of Ben Cosgrove and Iwijn De Vlaminck at Cornell University. This position will develop and apply novel spatial total RNA-sequencing technologies to study skeletal muscle regeneration and disease. Recent collaborative advances by the De Vlaminck and Cosgrove laboratories have developed new approaches for studying muscle regeneration (De Micheli et al, Cell Reports, 2020) and cardiac infection biology (Mantri et al, Nature Cardiovascular Research, 2022) at the single-cell level. Our labs have built novel technologies for spatial profiling of the total transcriptome through in situ polyadenylation to achieve unprecedented complexity and resolution of non-coding and viral RNA species (McKellar et al, Nature Biotechnology, 2022). Further, we have exploited single-cell and spatial transcriptomics analyses to generate large-scale data atlases of skeletal muscle regeneration to explore the spatial context of cell-cell communication (McKellar et al, Communications Biology, 2021).

This position will play a central role in several multi-PI collaborative projects with the goal of applying total transcriptomic profiling in single-cell and spatial workflows to study human and skeletal muscle development and disease pathogenesis. This work will entail genomic and transcriptomic technology development and application and a suite of bioinformatic data analyses. Applicants are not required to have expertise in all of these specific skills, but do need a familiarity with quantitative and/or computational aspects of biology. These research projects are supported by multiple grants from the National Institutes of Health and the Chan Zuckerberg Initiative. Supervisors will actively support the candidate’s applications for postdoctoral training fellowship, including internal training grant opportunities. This will be a one-year appointment, with annual extension possible based on satisfactory performance.

Required Qualifications: • PhD or equivalent degree completed by the start of the position • Training in biomedical science, molecular/cellular biology, biomedical engineering, computational biology, biophysics, or related disciplines • Experience in quantitative or computational biology

Application Materials Required: • Curriculum vitae • A short statement describing (i) your research experiences to date and (ii) your particular interests in and (iii) your qualifications related to this position (no more than 1 page in length) • Examples of your research publications as attachments (up to 3) • Contact information for academic references (up to 3)

Logistics: • Employer: Cornell University • Location: Ithaca, NY • Start Date: Immediately • Application Deadline: None, though applications will be reviewed on a rolling basis until the position is filled. • Length of Appointment: 1 year with potential for annual renewal with satisfactory performance • Time commitment: Full Time

Institution Climate:

Diversity and Inclusion are a part of our heritage. We are a recognized employer and educator valuing AA/EEO, Protected Veterans and Individuals with Disabilities. We also recognize a lawful preference in employment practices for Native Americans living on or near Indian reservations. Cornell University embraces diversity and seeks candidates who will contribute to a climate that supports students, faculty and staff of all identities and backgrounds. We strongly encourage individuals from underrepresented and/or marginalized identities to apply. Ithaca is located in the heart of the beautiful Finger Lakes region of upstate New York, known for its wines, waterfalls, craft beers, and unique blend of outdoors and cosmopolitan lifestyle. It has a high walkability index, strong public transit system, and low cost of living. Ithaca is regularly listed among the Top 100 Best Places to Live and Best Places for Entrepreneurs. The region is further home to multiple nationally-ranked State Parks.

Other Requirements:

As part of the university's comprehensive vaccination program, all Cornell employees are required to have and provide proof of an FDA-or WHO-authorized or approved COVID-19 primary vaccination or have obtained a university-approved disability/medical or religious exemption, regardless of their role and work location. New hires are required to provide documentation showing primary vaccination status (that is, completion of two shots of the Moderna or Pfizer vaccine or one shot of the Janssen/Johnson & Johnson) before their first day of work. If a new hire's vaccination is not complete or information is not received by their start date, the first day of work will be delayed. It is possible in some cases that an offer of employment may be withdrawn.

Contact Information:

Prof. Benjamin Cosgrove (bdc68@cornell.edu) & Prof. Iwijn De Vlaminck (id93@cornell.edu) Cornell University Meinig School of Biomedical Engineering 115 Weill Hall Ithaca, NY 14853-7207

As part of the university's comprehensive vaccination program , all Cornell employees are required to have and provide proof of an FDA-or WHO-authorized or approved COVID-19 primary vaccination or have obtained a university-approved disability/medical or religious exemption, regardless of their role and work location.

New hires are required to provide documentation showing primary vaccination status (that is, completion of two shots of the Moderna or Pfizer vaccine or one shot of the Janssen/Johnson & Johnson) before their first day of work. If a new hire's vaccination is not complete or information is not received by their start date, the first day of work will be delayed. It is possible in some cases that an offer of employment may be withdrawn.

Diversity and Inclusion are a part of Cornell University’s heritage. We are a recognized employer and educator valuing AA/EEO, Protected Veterans and Individuals with Disabilities. We also recognize a lawful preference in employment practices for Native Americans living on or near Indian reservations. Cornell University is an innovative Ivy League university and a great place to work. Our inclusive community of scholars, students, and staff impart an uncommon sense of larger purpose, and contribute creative ideas to further the university's mission of teaching, discovery, and engagement.