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Research Associate 1
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Research Associate 1
Medicine | IM Hematology
The Research Associate 1-B/H will participate in the planning, design, execution, and management of research projects in a foundational (basic) biological/health science research laboratory investigating cancer within the Comprehensive Cancer Center at the Ohio State University. The Research Associate in Immuno-Oncology will focus on Tumor Microenvironment and CAR T-cell.
Dr. Denlinger works within the context of the larger Yang lab overseen by Dr. Yiping Yang. The Yang lab focuses on immuno-oncology research, particularly the tumor microenvironment (TME) and how it influences T-cell-mediated anti-tumor immunity. Applications include in vitro work, mouse models, human studies, and clinical correlatives for novel clinical trial design. Within the Yang lab, Dr. Denlingerâ€™s work focused on the lymphoma TME, CAR T-cell therapy manufacturing, and phenotyping, and clinical correlatives focused on the development of novel cell therapies and optimizing by targeting the TME and improving CAR T-cell phenotyping.
Sample acquisition and preparation (in the lab and with human samples in the context of clinical trials) and sample indexing
Sample preparation for flow cytometry and single-cell RNA sequencing including viability and quality assessment, and performance of flow cytometry
Primary Data Analysis, assisting other members of the research team as needed, and assisting with grant/manuscript submissions
Assist with pre-clinical animal work including pre-clinical tumor models, genotyping, and assisting mouse colony maintenance
Participate in developing and implementing goals and objectives of studies
Design and execute complex laboratory experiments
Perform advanced molecular and cellular techniques
Collect, analyze and interpret research data
Assist with the development and implementation of new and/or revised research methodologies and techniques
Test experimental designs, sampling techniques, and analytical methods and make recommendations for utilization
Assist in the establishment of controls, criteria, and research standards
Perform a critical analysis of literature relevant to the research being undertaken
Assist in the preparation of research papers and manuscripts for publication and presentation at national conferences and workshops, and in the writing of project reports, articles, and other documents
Assist Principal Investigator in the preparation of proposals to obtain new or renewal of extramural funding in support of research
Coordinate laboratory activities and work assignments of postdoctoral researchers, graduate and undergraduate students, and laboratory research staff
Oversee and coordinate periodic maintenance and testing of laboratory equipment
Perform additional duties as assigned
Minimum Education Required:Â
Master's degree in an appropriate biological/health science OR an equivalent combination of education and experience is required
Experience in performing techniques such as sample and tissue preparation, single cell suspension prep, viable cryopreservation and thawing, and flow cytometry is preferred
Ability to translate, adapt, and apply academic and/or practical knowledge in the conduct of biological/health science research is required
Experience in a biological/health science research capacity is required
Requires successful completion of a background check
The candidate may be asked to complete a pre-employment physical, including a drug screen
The Ohio State University is a dynamic community of diverse resources, where opportunity thrives and where individuals transform themselves and the world. The Ohio State University is one of the nationâ€™s largest and most comprehensive public universities and a top employer in Ohio.
As one of only 50 designated comprehensive cancer centers in the nation, The Ohio State University Comprehensive Cancer Center â€“ Arthur G. James Cancer Hospital and Richard J. Solove Research Institute is dedicated to the creation of knowledge in laboratory, clinical and population-based cancer research. We apply those discoveries to develop more effective approaches to cancer prevention, diagnosis, and therapies â€“ providing tomorrowâ€™s standard of care today.Â A Cancer-Free World Begins Here.Â
The OSUCCC â€“ James is the only cancer program in the United States that features a National Cancer Institute (NCI)-designated comprehensive cancer center aligned with a nationally ranked academic medical center and a freestanding cancer hospital on the campus of one of the nationâ€™s largest public universities. is the only cancer program in the United States that features a National Cancer Institute (NCI)-designated comprehensive cancer center aligned with a nationally ranked academic medical center and a freestanding cancer hospital on the campus of one of the nationâ€™s largest public universities.
As an Ohio State employee, you will also have access to many benefits such as
Retirement Package choice of OPERS or Alternative Retirement Plan
Competitive Vacation and Sick Leave Program
11 Paid Holidays per year
Dental and Vision Insurance
Opportunity to purchase season tickets to OSU sporting events
Additional discounted rates on things such as select cell phone plans, pet care, food, dining, etc.
The Targeted Pay Range:Â $42,700-56,900 per year.
By the start of employment, all newly hired employees must receive at least the first dose of a two-dose series or a single dose of a one-dose series COVID-19 vaccination. Individuals who choose a two-dose series vaccination must receive the second dose within 45 days of their start date. Proof of vaccination will be required at time of hire.
Candidates may request a medical or religious exemption from the vaccination requirement. Campus employees may also request an exemption for personal reasons. Ohio State Wexner Medical Center, College of Medicine or OSUP Employees are not eligible for personal exemptions. All exemptions are subject to Ohio Stateâ€™s approval and subject to change, including revocation, due to legal and regulatory requirements.
Biomedical Research Tower (0112)
Final candidates are subject to successful completion of a background check. Â A drug screen or physical may be required during the post offer process.
Thank you for your interest in positions at The Ohio State University and Wexner Medical Center. Once you have applied, the most updated information on the status of your application can be found by visiting the Candidate Home section of this site. Please view your submitted applications by logging in and reviewing your status. For answers to additional questions please review the frequently asked questions .
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All qualified applicants will receive consideration for employment without regard to age, ancestry, color, disability, ethnicity, gender identity or expression, genetic information, HIV/AIDS status, military status, national origin, race, religion, sex, gender, sexual orientation, pregnancy, protected veteran status, or any other basis under the law.
Applicants are encouraged to complete and submit the Equal Employment Identification form.
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