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Computational Biology

Job Description


Mentor: Dr. Chen Huang, Genetics Research Division

Postdoc Employee:

Dr. Chen Huang’s laboratory ( at the University of Alabama at Birmingham (UAB) is recruiting postdoc fellows in Computational Biology. The Huang lab strives for mechanistic understanding and therapeutic insights of cancer and other complex diseases by extensively exploring large-scale multiomics data. We are particularly interested in coupling the next generation sequencing based genomics and mass spectrometry-based proteomics to characterize disease genomic abnormalities and interpret their functional outcomes seamlessly. Several immediate projects to be tackled include 1) tumor antigens 2) proteomics-driven cellular pathway interpretation 3) interpatient cancer heterogeneity and precision oncology. Our ways to conduct fruitful basic and translational research involve developing novel bioinformatic tools, performing integrative data analysis and collaborating with experimental biologists and clinicians. The PI was trained as an experimental and computational biologist and has strong productivity on both sides. During Ph.D. and postdoc, Dr. Huang has first/cofirst-authored papers in Dev Cell (2018 and 2020), Cancer Cell (2021), and Cell (2019 and 2021) and middle-authored multiple others in top-tier journals. Together with nationwide collaborators, our lab is committed to guide trainees to develop strong research expertise and carve successful career paths. 

We welcome motivated fresh graduates to join us for our brand-new scientific journey. Ideal candidates would have:

1) Proficiency in programming with R and/or python.

2) Self-motivation and strong interests in biology and data sciences, open mind, and abilities in fast learning.

The following background would be considered as a plus:

1) Hands-on experience in machine learning and deep learning.

2) Knowledge and experience in processing MS proteomics, scRNA-seq or long read seq data.

3) Demonstrated research achievements in bioinformatics.

The positions are for 2-3 years with possible extension. We provide competitive salaries and benefits. The salary will be based or above the NIH guidance (commensurate with experience).  To apply, please send an email to Dr. Huang (This email address is being protected from spambots. You need JavaScript enabled to view it. with current CV and contacts for 2-3 references, and a brief description of training background and career plans.

We are located in downtown Birmingham, a city with marvelous beauty of nature and low cost of living. UAB is ranked #20 of all U.S. institutions and universities in annual NIH funding. UAB School of Medicine is ranked constantly within the 30th place for research in US Best Medical Schools. The laboratory is affiliated to the Department of Genetics and the O’Neal’s Cancer Center, both of which are loaded with great momentum and ambitious growth plans in the coming years.

 Primary Location: University- On Site/ Hybrid Possible

Job Category: Scientific Research

Organization Number Genetics 392704000

Employee Status: Regular

Shift: Day/1st Shift

About our Postdoc Office

UAB is committed to the development and success of outstanding postdoctoral scientists. Here at UAB, nearly 300 postdoctoral fellows are training currently in a variety of disciplines. Competitive postdoc awards are available including internships, grant incentives, funds to enhance education and collaboration outside UAB, and teaching opportunities at local universities. There is also a Postdoc Research Day with monetary awards. The Office of Postdoctoral Education strongly encourages UAB research mentors to follow the National Research Service Award stipend level guidelines, and postdoctoral scholars qualify for health, life, and other insurances. They also have the right to participate in the university’s 403(b) program and enjoy vacation, sick leave, maternity/paternity leave, and other benefits.

About the University

The University of Alabama at Birmingham (UAB) is a research university and academic health center that discovers, teaches, and applies knowledge for the intellectual, cultural, social, and economic benefit of Birmingham, the state, and beyond. UAB is internationally renowned for its intensely collaborative culture that has — for more than five decades — produced breakthroughs in education, health care, research, and service. UAB was ranked #1 in the United States, and in the top 10 worldwide, in the Times Higher Education World University Rankings, 2018 Young University Rankings.

Spanning more than 100 city blocks, UAB is the state of Alabama’s largest single employer with over 26,000 employees and has an annual state-wide economic impact exceeding $7.15 billion. U.S. News & World Report’s 2020 “America’s Best Graduate Schools” ranks 14 UAB graduate programs among the nation’s top 25 and 10 UAB specialties were ranked among the nation’s top 50 in the magazine’s 2018-2019 Best Hospitals report. UAB research grants and awards are at a record high, exceeding $527 million in FY18, including $320 million in NIH funding for FY18. UAB ranks 31st among all universities in federal research funding and 15th among public universities. UAB's NIH funding continues to grow among peer institutions in the Southeast and beyond, with the university ranking 20th among all universities in NIH funding and eighth among public universities. The UAB Heersink School of Medicine is ranked 21st among medical schools in NIH funding and eighth among public medical schools.

UAB is an Equal Opportunity/Affirmative Action Employer committed to fostering a diverse, equitable and family-friendly environment in which all faculty and staff can excel and achieve work/life balance irrespective of, race, national origin, age, genetic or family medical history, gender, faith, gender identity, and expression as well as sexual orientation. UAB also encourages applications from individuals with disabilities and veterans.

For more information on Equal Opportunity and Affirmative Action at UAB, visit the UAB Office of Diversity, Equity and Inclusion opens a new website, call (205) 934-8762, or contact the office at 701 20th Street South, AB 336, Birmingham, AL 35294-0103.

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