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Pediatrics

Job Description

I220601

Mentor: Dr. Jennifer Guimbellot, Department of Pediatrics

Post-Doctoral Laboratory Position in the Department of Pediatrics

This open post-doctoral position will be in the research group of Dr. Jennifer Guimbellot, in the Department of Pediatrics, Pulmonary and Sleep Medicine. The postdoctoral fellow will work on projects relating to the use of CFTR modulator therapy in patients with cystic fibrosis, to understand better how to personalize and optimize the use of the medications in children and adults with cystic fibrosis. These studies encompass three main areas:

  • Understand the pharmacokinetic variability of CFTR modulators in the blood and in the target tissue during typical clinical use and how that may impact response
  • Evaluate potential for pharmacogenomics variants to impact CFTR modulator concentration or response
  • Identify the mechanisms of CFTR modulator therapy in promoting optimal health and growth in individuals with cystic fibrosis

Additional projects examining aspects of these three main areas are available. In collaboration with other colleagues at UAB, Dr. Guimbellot uses non-compartmental analysis, generalized linear mixed modeling, non-linear mixed effects modeling, with planned gene-centered association studies to complete these projects. For the interestesd candidate, experience in clinical research including interaction with research participants

Responsibilities include:

  • Help generate new projects by developing and submitting grant applications and proposals.
  • Initiate and maintain collaborator relationships, with research service providers, and other relevant research entities.
  • Develop projects to include participating in research design, identifying participants, determining data elements, selecting or developing measurement tools, and completing deliverables.
  • Maintain the integrity of sampling and data collection efforts.
  • Data analysis, including graphical representations of the data, preparation of datasets for statistical analysis, and descriptive analysis, reviewing quantitative data output for accuracy.
  • Develop, submit, and present conference presentations and help publish manuscripts.

Qualifications:

Candidate required to have a PharmD or PhD in a related field. Candidate should have experience with electronic medical records, data collection, basic analysis, and scientific writing. Interest in additional training is desired, which would include training in clinical research project management, clinical pharmacology analyses, data analysis, grant writing, and scientific writing. The ideal candidate will have strong skills in written communication with scrupulous attention to detail. Candidates will be required to apply for a post-doctoral research fellowship award during the first year of the appointment.

How to apply:

Please submit a curriculum vita, a cover letter describing your research background, interests, and career goals, and contact information for three references to Dr. Guimbellot.

 

Jennifer S. Guimbellot MD, PhD | Associate Professor

Division of Pulmonary and Sleep Medicine

Department of Pediatrics

Scientist

UAB Cystic Fibrosis Research Center

UAB Lung Health Research Center

UAB | The University of Alabama at Birmingham

P: 205.6389583 | This email address is being protected from spambots. You need JavaScript enabled to view it.

About our Postdoc Office

UAB is committed to the development and success of outstanding postdoctoral scientists. Here at UAB, nearly 300 postdoctoral fellows are training currently in a variety of disciplines. Competitive postdoc awards are available including internships, grant incentives, funds to enhance education and collaboration outside UAB, and teaching opportunities at local universities. There is also a Postdoc Research Day with monetary awards. The Office of Postdoctoral Education strongly encourages UAB research mentors to follow the National Research Service Award stipend level guidelines, and postdoctoral scholars qualify for health, life, and other insurances. They also have the right to participate in the university’s 403(b) program and enjoy vacation, sick leave, maternity/paternity leave, and other benefits.

About the University

The University of Alabama at Birmingham (UAB) is a research university and academic health center that discovers, teaches, and applies knowledge for the intellectual, cultural, social, and economic benefit of Birmingham, the state, and beyond. UAB is internationally renowned for its intensely collaborative culture that has — for more than five decades — produced breakthroughs in education, health care, research, and service. UAB was ranked #1 in the United States, and in the top 10 worldwide, in the Times Higher Education World University Rankings, 2018 Young University Rankings.

Spanning more than 100 city blocks, UAB is the state of Alabama’s largest single employer with over 26,000 employees and has an annual state-wide economic impact exceeding $7.15 billion. U.S. News & World Report’s 2020 “America’s Best Graduate Schools” ranks 14 UAB graduate programs among the nation’s top 25 and 10 UAB specialties were ranked among the nation’s top 50 in the magazine’s 2018-2019 Best Hospitals report. UAB research grants and awards are at a record high, exceeding $527 million in FY18, including $320 million in NIH funding for FY18. UAB ranks 31st among all universities in federal research funding and 15th among public universities. UAB's NIH funding continues to grow among peer institutions in the Southeast and beyond, with the university ranking 20th among all universities in NIH funding and eighth among public universities. The UAB Heersink School of Medicine is ranked 21st among medical schools in NIH funding and eighth among public medical schools.

UAB is an Equal Opportunity/Affirmative Action Employer committed to fostering a diverse, equitable and family-friendly environment in which all faculty and staff can excel and achieve work/life balance irrespective of, race, national origin, age, genetic or family medical history, gender, faith, gender identity, and expression as well as sexual orientation. UAB also encourages applications from individuals with disabilities and veterans.

For more information on Equal Opportunity and Affirmative Action at UAB, visit the UAB Office of Diversity, Equity and Inclusion opens a new website, call (205) 934-8762, or contact the office at 701 20th Street South, AB 336, Birmingham, AL 35294-0103.

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